1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CXCR
  4. CXCR1 Inhibitors

CXCR1 Inhibitors

CXCR

CXCR1

CXCR2

CXCR3

CXCR4

CXCR7

CX3CR1

CXCR8

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CXCR1 together.

Please try each isoform separately.

CXCR1 Specific Inhibitors & Antagonists
Product Name CXCR1 CXCR2 CXCR1 Selectivity Purity
Reparixin
CXCR1wt, IC50: 5.6 nM (in L1.2 cells)
CXCR1Ile43Val, IC50: 80 nM (in L1.2 cells)
CXCR1, IC50: 1 nM (in cells)
CXCR2, IC50: ∼100 nM (in cells)
Selective Inhibitor 99.98%
Reparixin L-lysine salt
CXCR1wt, IC50: 5.6 nM (in L1.2 cells)
CXCR1Ile43Val, IC50: 80 nM (in L1.2 cells)
CXCR1, IC50: 1 nM (in cells)
CXCR2, IC50: ∼100 nM (in cells)
Selective Inhibitor 99.97%
Navarixin
Cynomolgus CXCR1, Kd: 41 nM
Mouse CXCR2, Kd: 0.2 nM
Rat CXCR2, Kd: 0.2 nM
Cynomolgus CXCR2, Kd: 0.08 nM
Pan Antagonist 98.62%
SCH 563705
CXCR1, Ki: 3 nM
CXCR1, IC50: 7.3 nM
CXCR2, Ki: 1 nM
CXCR2, IC50: 1.3 nM
Mouse CXCR2, IC50: 5.2 nM
Pan Antagonist 95.34%
SX-682
CXCR1
CXCR2
Pan Inhibitor