1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CXCR
  4. CXCR2 Inhibitors

CXCR2 Inhibitors

CXCR

CXCR1

CXCR2

CXCR3

CXCR4

CXCR7

CX3CR1

CXCR8

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CXCR2 together.

Please try each isoform separately.

CXCR2 Specific Inhibitors & Antagonists
Product Name CXCR2 CXCR1 CX3CR1 CXCR2 Selectivity Purity
SB225002
125I-IL-8-CXCR2, IC50: 22 nM (in CHO cell membrane)
    Selective Antagonist 99.78%
Navarixin
Mouse CXCR2, Kd: 0.2 nM
Rat CXCR2, Kd: 0.2 nM
Cynomolgus CXCR2, Kd: 0.08 nM
Cynomolgus CXCR1, Kd: 41 nM
  Selective Antagonist 98.62%
AZD-5069
125I-IL-8-CXCR2
    Selective Antagonist 99.92%
Danirixin
CXCL8-CXCR2, IC50: 12.5 nM
    Selective Antagonist 98.21%
CXCR2-IN-1
CXCR2, pIC50: 9.3
    Selective Inhibitor 98.81%
SRT3109
CXCR2, pIC50: 8.2
    Selective Antagonist 99.82%
SRT3190
CXCR2
    Selective Antagonist 99.61%
Reparixin
CXCR2, IC50: ∼100 nM (in cells)
CXCR1wt, IC50: 5.6 nM (in L1.2 cells)
CXCR1Ile43Val, IC50: 80 nM (in L1.2 cells)
CXCR1, IC50: 1 nM (in cells)
  Pan Inhibitor 99.98%
AZD8797
125I-IL-8-CXCR2, Ki: 2800 nM (in HEK293S cells)
 
[125I]-CX3CL1-CX3CR1, Ki: 3.9 nM (in HEK293S cells)
Pan Antagonist 98.22%
Reparixin L-lysine salt
CXCR2, IC50: ∼100 nM (in cells)
CXCR1wt, IC50: 5.6 nM (in L1.2 cells)
CXCR1Ile43Val, IC50: 80 nM (in L1.2 cells)
CXCR1, IC50: 1 nM (in cells)
  Pan Inhibitor 99.97%
SCH 563705
CXCR2, Ki: 1 nM
CXCR2, IC50: 1.3 nM
Mouse CXCR2, IC50: 5.2 nM
CXCR1, Ki: 3 nM
CXCR1, IC50: 7.3 nM
  Pan Antagonist 95.34%
SX-682
CXCR2
CXCR1
  Pan Inhibitor