1. GPCR/G Protein Immunology/Inflammation
  2. CXCR
  3. Danirixin

Danirixin  (Synonyms: GSK1325756)

Cat. No.: HY-19768 Purity: 98.45%
COA Handling Instructions

Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

For research use only. We do not sell to patients.

Danirixin Chemical Structure

Danirixin Chemical Structure

CAS No. : 954126-98-8

Size Price Stock Quantity
1 mg USD 100 In-stock
5 mg USD 300 In-stock
10 mg USD 425 In-stock
50 mg USD 1300 In-stock
100 mg USD 1750 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 6 publication(s) in Google Scholar

Top Publications Citing Use of Products

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Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

IC50 & Target[1]


12.5 nM (IC50)

In Vitro

Danirixin is a small molecule, CXCR2 antagonist being evaluated as a potential anti-inflammatory medicine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 8 mg/mL (18.10 mM; Need ultrasonic and warming)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2630 mL 11.3148 mL 22.6296 mL
5 mM 0.4526 mL 2.2630 mL 4.5259 mL
10 mM 0.2263 mL 1.1315 mL 2.2630 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Danirixin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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