CSNK1D/CK1d
Casein kinase 1 delta (CK1δ, gene CSNK1D) is best known as a core circadian timer: it phosphorylates PER1 and PER2 proteins, controlling their stability and the period length of the transcription-translation feedback loop. Human CSNK1D variants that alter PER2 phosphorylation cause familial advanced sleep phase syndrome. Beyond the clock, CK1δ acts in Wnt signaling, p53 regulation, microtubule dynamics and neuronal function, and it is expressed in most tissues with enrichment in brain. Together with its close paralog CK1ε, it defines the δ/ε branch of the CK1 family and is a validated target for circadian and cancer therapeutics.
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CSNK1D/CK1d Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
