ICAM-2/CD102
ICAM-2 (CD102) is a compact member of the intercellular adhesion molecule family, carrying only two extracellular immunoglobulin-like domains in contrast to the five domains of ICAM-1. It is a ligand for the leukocyte integrins LFA-1 (αLβ2) and Mac-1 (αMβ2). Unlike inducible ICAM-1, ICAM-2 is constitutively expressed at high levels on resting endothelium and is concentrated at endothelial cell junctions, providing a baseline adhesion platform for circulating leukocytes. It also resides on platelets and most leukocytes. Through these interactions CD102 supports leukocyte trafficking across resting vessels and contributes to immune surveillance, and its cytoplasmic tail contributes to endothelial junctional organization.
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ICAM-2/CD102 Recombinant Proteins (5)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
