P-Selectin/CD62P
P-Selectin, the CD62P antigen encoded by SELP, resides preformed in platelet α-granules and endothelial Weibel-Palade bodies and is translocated to the plasma membrane within minutes of agonist stimulation, providing the fastest selectin response in vascular biology. Its lectin domain engages PSGL-1 on myeloid cells and platelets, mediating rolling interactions that bridge coagulation and inflammation, and it participates in tumor cell-platelet aggregates that facilitate metastasis. Unlike E-selectin, P-selectin can return to storage granules via endocytosis. Soluble P-selectin in plasma reflects platelet activation and is monitored in thrombotic risk research.
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P-Selectin/CD62P Recombinant Proteins (10)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
