M-CSF R
Macrophage colony-stimulating factor receptor (M-CSFR, CSF1R, CD115) is a class III receptor tyrosine kinase expressed on monocytes, macrophages and their progenitors, as well as Langerhans cell precursors. Binding of its ligands M-CSF and IL-34 induces receptor homodimerization and trans-autophosphorylation of the intracellular kinase domain, activating SRC family kinases, PI3K-AKT, MAPK and STAT3 pathways that deliver survival, proliferation and differentiation signals to the mononuclear phagocyte lineage. M-CSFR signaling specifies macrophage fate from common myeloid progenitors, supports osteoclast generation and bone resorption together with RANKL, and sustains tissue-resident macrophages and microglia. Loss-of-function CSF1R mutations cause hereditary diffuse leukoencephalopathy with axonal spheroids, while receptor overactivation contributes to chronic inflammation, atherosclerosis and tumor-associated macrophage accumulation; CSF1R inhibitors are clinically approved for tenosynovial giant cell tumors.
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M-CSF R Recombinant Proteins (24)
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Inhibitors & Agonists (154)
CSF1R Protein, Mouse (HEK293, His)
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Cat. No.: HY-P72952
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293)
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Cat. No.: HY-P72948
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macrophage Colony-Stimulating Factor 1 Receptor; CSF-1-R; Proto-Oncogene C-Fms; HDLS1; CSF-1 Receptor; FIM2; CD115 Antigen; GPSC; M-CSF-R; HDLS; Colony Stimulating Factor 1 Receptor; Platelet-Derived Growth Factor Receptor-Like Protein
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CSF1R Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P72951
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293, C-His-Avi)
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Cat. No.: HY-P73510
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293, His-Fc)
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Cat. No.: HY-P75323
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macrophage Colony-Stimulating Factor 1 Receptor; CSF-1-R; Proto-Oncogene C-Fms; HDLS1; CSF-1 Receptor; FIM2; CD115 Antigen; GPSC; M-CSF-R; HDLS; Colony Stimulating Factor 1 Receptor; Platelet-Derived Growth Factor Receptor-Like Protein
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CSF1R Protein, Mouse (Biotinylated, HEK293, His)
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Cat. No.: HY-P72953
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macrophage Colony-Stimulating Factor 1 Receptor; CSF-1-R; Proto-Oncogene C-Fms; HDLS1; CSF-1 Receptor; FIM2; CD115 Antigen; GPSC; M-CSF-R; HDLS; Colony Stimulating Factor 1 Receptor; Platelet-Derived Growth Factor Receptor-Like Protein
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CSF1R Protein, Human (HEK293, hFc, SPR verified)
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Cat. No.: HY-P72949U
Purity: ≥ 95%, as determined by reducing SDS-PAGE.; ≥ 95%, as determined by HPLC.
Synonyms: Macrophage colony-stimulating factor 1 receptor; CSF-1R; M-CSF-R; CD115; CSF1R; FMS
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CSF1R Protein, Rat (HEK293, His, solution)
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Cat. No.: HY-P72955
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293, His)
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Cat. No.: HY-P72509
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Cynomolgus (HEK293, Fc)
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Cat. No.: HY-P70124
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Rhesus Macaque (C378R, HEK293, His)
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Cat. No.: HY-P76295
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Rat (HEK293, C-His)
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Cat. No.: HY-P72955A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293, hFc)
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Cat. No.: HY-P72949
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (HEK293, mFc)
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Cat. No.: HY-P72950
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Mouse (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78892
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Rat (HEK293, Fc)
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Cat. No.: HY-P72954
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Canine (HEK293, His)
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Cat. No.: HY-P78637
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (271a.a, HEK293, His)
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Cat. No.: HY-P75326
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (214a.a, HEK293, His)
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Cat. No.: HY-P75327
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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CSF1R Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78109
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
