SCY1
SCYL1, SCYL2 and SCYL3 make up the SCY1 family, a group of Sif1/Yot-like kinases whose names derive from yeast suppressors of cell-cycle defects. SCYL1 associates with COPI-coated vesicles and participates in Golgi-to-ER retrograde transport; recessive loss-of-function mutations in SCYL1 cause a spinocerebellar ataxia with peripheral neuropathy and episodic liver failure. SCYL2, also known as CVAK104, is a clathrin-associated kinase implicated in vesicle trafficking and in endosomal sorting. SCYL3 has an atypical catalytic domain and is expressed in hematopoietic tissues with no firmly established function. Together these members illustrate how little is known about trafficking-linked kinase branches of the kinome.
-
SCY1 Recombinant Proteins (2)
- Species:
- Source:
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
