Signaling Pathway

Influenza Virus

Influenza Virus

Related Products

PDF File 0.28MB

Influenza virus belong to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Influenza Virus Inhibitors & Modulators (17)

Product Name Catalog No. Brief Description
Amantadine hydrochloride


Amantadine Hydrochloride is an antiviral and an antiparkinsonian drug.



Aprotinin is a 58 Amino Acid peptide protease inhibitor, used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation.

Arbidol hydrochloride


Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane
IC50 value:
Target: Antiviral; Anti-influenza agent
in vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.



Dehydroandrographolide is extracted from herbal medicine Andrographis paniculata (Burm f) Nees; alleviate oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS.

M2 ion channel blocker


This compound is capable of inhibiting and blocking the activity of M2 ion channel.

Moroxydine hydrochloride


Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.



Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.

Nitazoxanide D4


Nitazoxanide D4 is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.



Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.

Oseltamivir acid


Oseltamivir acid (GS 4071; Ro 64-0802) is a metabolite of Oseltamivir.

Oseltamivir phosphate


Oseltamivir phosphate (GS-4104) is a competitive neuraminidase inhibitor, which is an antiviral drug.



Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.

Peramivir trihydrate


Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.



Rimantadine (Flumadine) is an anti-influenza virus drug.

Rimantadine hydrochloride


Rimantadine Hcl (Flumadine) is an anti-influenza virus drug.



Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.



Zanamivir is an influenza viral neuraminidase inhibitor that is a structural analog of the sialic acid.