1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Influenza Virus Related Products (36):

Cat. No. Product Name Effect Purity
  • HY-13318
    Oseltamivir acid Inhibitor 98.60%
    GS 4104, the ethyl ester prodrug of GS 4071, is an inhibitor of influenza virus neuraminidase with an IC50 of approximately 100 nM.
  • HY-P0017
    Aprotinin Inhibitor
    Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with Kis of 0.06 pM and 9 nM, respectively.
  • HY-109025A
    Baloxavir Inhibitor 99.71%
    Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1.
  • HY-101950
    KIN1148 Inhibitor >98.0%
    KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.
  • HY-12353A
    Pimodivir Inhibitor 99.04%
    Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.
  • HY-111802
    3,4'-Dihydroxyflavone Inhibitor 98.20%
    3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus.
  • HY-14818
    Laninamivir Inhibitor
    Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively.
  • HY-122907
    JNJ4796 Inhibitor
    JNJ4796 is an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
  • HY-17016
    Oseltamivir phosphate Inhibitor 99.85%
    Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
  • HY-B0217
    Nitazoxanide Inhibitor
    Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.
  • HY-13210
    Zanamivir Inhibitor 99.59%
    Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively.
  • HY-14904A
    Arbidol hydrochloride Inhibitor 99.44%
    Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane
  • HY-50001
    Nucleozin Inhibitor 99.45%
    Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
  • HY-N0243
    Theaflavin Inhibitor 99.09%
    Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
  • HY-B0402A
    Amantadine hydrochloride Inhibitor >98.00%
    Amantadine Hydrochloride is an antiviral and an antiparkinsonian drug.
  • HY-107902
    RIG-1 modulator 1 Inhibitor 98.81%
    RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.
  • HY-17015
    Peramivir trihydrate Inhibitor 99.91%
    Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
  • HY-W015346
    Desaminotyrosine Inhibitor 99.32%
    Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
  • HY-U00160
    SP187 Inhibitor 99.30%
    SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
  • HY-B0338A
    Rimantadine hydrochloride Inhibitor >98.0%
    Rimantadine Hcl (Flumadine) is an anti-influenza virus drug.
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