1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Influenza Virus Related Products (64):

Cat. No. Product Name Effect Purity
  • HY-N0005
    Curcumin Inhibitor 99.66%
    Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.
  • HY-109025A
    Baloxavir Inhibitor 99.71%
    Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1.
  • HY-13318
    Oseltamivir (acid) Inhibitor 99.54%
    Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses.
  • HY-P0017
    Aprotinin Inhibitor
    Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with Kis of 0.06 pM and 9 nM, respectively.
  • HY-109025
    Baloxavir marboxil Inhibitor 99.95%
    Baloxavir marboxil is a small molecule inhibitor of the cap-dependent endonuclease of influenza A and B viruses.
  • HY-14768
    Favipiravir Inhibitor 98.50%
    Favipiravir (T-705) is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50 of 341 nM.
  • HY-10496
    SC75741 Inhibitor 99.51%
    SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication in non-toxic concentrations. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.
  • HY-N0224
    Epigoitrin Inhibitor 99.91%
    Epigoitrin is a natural alkaloid from Isatis indigotica, with antiviral activities. Epigoitrin reduces susceptibility to influenza virus via mitochondrial antiviral signaling.
  • HY-12821
    AEBSF hydrochloride Inhibitor 99.76%
    AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
  • HY-N0196
    Baicalein Inhibitor >98.0%
    Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM.
  • HY-17016
    Oseltamivir phosphate Inhibitor 99.85%
    Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
  • HY-12353A
    Pimodivir Inhibitor 99.04%
    Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.
  • HY-101950
    KIN1148 Inhibitor >98.0%
    KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.
  • HY-13210
    Zanamivir Inhibitor 99.59%
    Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively.
  • HY-12054
    Hesperadin Inhibitor 98.48%
    Hesperadin is an ATP-competitive inhibitor of aurora B kinase with an IC50 of 250 nM.
  • HY-B0217
    Nitazoxanide Inhibitor 98.03%
    Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.
  • HY-B0532A
    Trifluoperazine dihydrochloride Inhibitor >99.0%
    Trifluoperazine Dihydrochloride is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
  • HY-N0898
    Catechin Inhibitor 99.23%
    Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
  • HY-N0009
    Geniposide Inhibitor 99.52%
    Geniposide is an iridoid glucoside extracted from Gardenia jasminoides Ellis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.
  • HY-N0243
    Theaflavin Inhibitor 99.09%
    Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
Isoform Specific Products

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