1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Influenza Virus Related Products (53):

Cat. No. Product Name Effect Purity
  • HY-13318
    Oseltamivir (acid) Inhibitor 99.54%
    Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate (Tamiflu), is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses.
  • HY-109025A
    Baloxavir Inhibitor 99.71%
    Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1.
  • HY-P0017
    Aprotinin Inhibitor
    Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with Kis of 0.06 pM and 9 nM, respectively.
  • HY-109025
    Baloxavir marboxil Inhibitor 99.95%
    Baloxavir marboxil is a small molecule inhibitor of the cap-dependent endonuclease of influenza A and B viruses.
  • HY-17016
    Oseltamivir phosphate Inhibitor 99.85%
    Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
  • HY-14768
    Favipiravir Inhibitor 98.89%
    Favipiravir (T-705) is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50 of 341 nM.
  • HY-10496
    SC75741 Inhibitor 99.51%
    SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication in non-toxic concentrations. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.
  • HY-111802
    3,4'-Dihydroxyflavone Inhibitor 98.20%
    3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus.
  • HY-12353A
    Pimodivir Inhibitor 99.04%
    Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.
  • HY-101950
    KIN1148 Inhibitor >98.0%
    KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.
  • HY-13210
    Zanamivir Inhibitor 99.59%
    Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively.
  • HY-B0217
    Nitazoxanide Inhibitor
    Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.
  • HY-14904A
    Arbidol hydrochloride Inhibitor 99.44%
    Arbidol hydrochloride (Umifenovir hydrochloride) is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane IC50 value: Target: Antiviral; Anti-influenza agent in vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.
  • HY-N0243
    Theaflavin Inhibitor 99.09%
    Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
  • HY-B0402A
    Amantadine hydrochloride Inhibitor >98.00%
    Amantadine Hydrochloride is an antiviral and an antiparkinsonian drug.
  • HY-50001
    Nucleozin Inhibitor 99.74%
    Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
  • HY-17015
    Peramivir trihydrate Inhibitor 99.40%
    Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.
  • HY-107902
    RIG-1 modulator 1 Inhibitor 98.81%
    RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.
  • HY-W015346
    Desaminotyrosine Inhibitor 99.32%
    Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
  • HY-B2226
    Sodium copper chlorophyllin B Inhibitor
    Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV with IC50s of 50 to 100 μM for both of them.
Isoform Specific Products

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