Akt2

Akt2 Related Products (42)
Recombinant Proteins (1)

By Type:	Pan (37) Selective (4)

Cat. No.	Product Name	Effect	Purity

HY-10358

MK-2206 dihydrochloride	Inhibitor	99.92%
MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active allosteric AKT inhibitor with IC₅₀s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively.

HY-15431

Capivasertib	Inhibitor	99.83%
Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC₅₀ of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.

HY-15186

Ipatasertib	Inhibitor	99.88%
Ipatasertib (GDC-0068) is a highly selective and ATP-competitive pan-Akt inhibitor with IC₅₀s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.

HY-10249

GSK-690693	Inhibitor	98.46%
GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC₅₀s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively.

HY-N0004

Oridonin	Inhibitor	99.89%
Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC₅₀s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.

HY-151504

ALM301	Inhibitor	99.33%
ALM301 is an orally active highly specific AKT inhibitor with IC₅₀ values of 0.13 µM, 0.09 µM and 2.75 µM for AKT1, AKT2 and AKT3, respectively.

HY-151613

MS15	Inhibitor
MS15 is a potent and selective AKT PROTAC degrader.

HY-133120A

INY-03-041 trihydrochloride

Inhibitor

99.27%

INY-03-041 trihydrochloride is a potent, highly selective and PROTAC-based pan-AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib (HY-15186) conjugated to HY-10355

AKT inhibitor VIII	Inhibitor	98.97%
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC₅₀s of 58 nM, 210 nM, and 2119 nM, respectively.

HY-19719

Miransertib	Inhibitor	99.33%
Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC₅₀s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.

HY-15727

Afuresertib	Inhibitor	99.54%
Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K_is of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively.

HY-15965

Uprosertib	Inhibitor	99.43%
Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC₅₀ values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.

HY-10425

A-443654	Inhibitor	98.50%
A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (K_i=160 pM).

HY-16071

AT13148	Inhibitor	99.42%
AT13148 is an orally active and ATP-competitive, multi-AGC kinase inhibitor with IC₅₀s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively.

HY-100018

BAY1125976	Inhibitor	99.74%
BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC₅₀ values of 5.2 nM and 18 nM at 10 μM ATP, respectively.

HY-15186A

Ipatasertib dihydrochloride	Inhibitor	99.27%
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC₅₀s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.

HY-13260

CCT128930	Inhibitor	99.69%
CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC₅₀=6 nM for AKT2).

HY-137458A

Vevorisertib trihydrochloride	Inhibitor	99.13%
Vevorisertib (ARQ 751) trihydrochloride is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors.

HY-19934A

TAS-117 hydrochloride	Inhibitor	98.96%
TAS-117 hydrochloride is a potent, selective, orally active allosteric Akt inhibitor (with IC₅₀s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively).

HY-12059

AT7867	Inhibitor	99.88%
AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC₅₀s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.

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Akt2

Akt2 Related Products (42)

Recombinant Proteins (1)

Akt2 Related Products (42):