1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. Akt
  4. Akt3 Inhibitors

Akt3 Inhibitors

Akt

Akt1

Akt2

Akt3

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Akt3 together.

Please try each isoform separately.

Akt3 Specific Inhibitors
Product Name Akt3 Akt Akt1 Akt2 Akt3 Selectivity Purity
MK-2206 dihydrochloride
Akt3, IC50: 65 nM
 
Akt1, IC50: 8 nM
Akt2, IC50: 12 nM
Pan Inhibitor 99.76%
Capivasertib
Akt3, IC50: 7 nM
 
Akt1, IC50: 3 nM
Akt2, IC50: 7 nM
Pan Inhibitor ≥98.0%
Ipatasertib
Akt3, IC50: 8 nM
 
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Pan Inhibitor ≥98.0%
TAS-117 hydrochloride
Akt3, IC50: 44 nM
 
Akt1, IC50: 4.8 nM
Akt2, IC50: 1.6 nM
Pan Inhibitor 98.96%
GSK-690693
Akt3, IC50: 9 nM
 
Akt1, IC50: 2 nM
Akt2, IC50: 13 nM
Pan Inhibitor 99.22%
AKT inhibitor VIII
Akt3, IC50: 2119 nM
 
Akt1, IC50: 58 nM
Akt2, IC50: 210 nM
Pan Inhibitor 98.93%
Miransertib
Akt3, IC50: 8.1 nM
 
Akt1, IC50: 2.7 nM
Akt2, IC50: 14 nM
Pan Inhibitor 99.33%
Afuresertib
Akt3, Ki: 2.6 nM
 
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Pan Inhibitor 99.86%
A-443654
Akt3, Ki: 160 pM
 
Akt1, Ki: 160 pM
Akt2, Ki: 160 pM
Pan Inhibitor 99.04%
Uprosertib
Akt3, IC50: 38 nM
 
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Pan Inhibitor 98.93%
Ipatasertib dihydrochloride
Akt3, IC50: 8 nM
 
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Pan Inhibitor 99.27%
AT13148
Akt3, IC50: 50 nM
 
Akt1, IC50: 38 nM
Akt2, IC50: 402 nM
Pan Inhibitor ≥98.0%
BAY1125976
Akt3, IC50: 427 nM (at 10 μM ATP)
 
Akt1, IC50: 5.2 nM (at 10 μM ATP)
Akt2, IC50: 18 nM (at 10 μM ATP)
Pan Inhibitor 99.86%
Afuresertib hydrochloride
Akt3, Ki: 2.6 nM
 
Akt1, Ki: 0.08 nM
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Pan Inhibitor 98.02%
AT7867
Akt3, IC50: 47 nM
 
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Pan Inhibitor ≥95.0%
M2698
Akt3, IC50: 1 nM
 
Akt1, IC50: 1 nM
  Pan Inhibitor ≥99.0%
AT7867 dihydrochloride
Akt3, IC50: 47 nM
 
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Pan Inhibitor 99.17%
MK-2206
Akt3, : 65 nM
 
Akt1, : 8 nM
Akt2, : 12 nM
Pan Inhibitor
Miransertib hydrochloride
Akt3, IC50: 8.1 nM
 
Akt1, IC50: 2.7 nM
Akt2, IC50: 174 nM
Pan Inhibitor
Hu7691 free base
Akt3, IC50: 28 nM
 
Akt1, IC50: 4.0 nM
Akt2, IC50: 97.5 nM
Pan Inhibitor
Hu7691
Akt3, IC50: 28 nM
 
Akt1, IC50: 4.0 nM
Akt2, IC50: 97.5 nM
Pan Inhibitor
AKT-IN-3
Akt3, IC50: 1.7 nM
 
Akt1, IC50: 1.4 nM
Akt2, IC50: 1.2 nM
Pan Inhibitor
INY-03-041
Akt3, IC50: 3.5 nM
 
Akt1, IC50: 2.0 nM
Akt2, IC50: 6.8 nM
Pan Inhibitor
Uprosertib hydrochloride
Akt3, IC50: 38 nM
 
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Pan Inhibitor