2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Carboxypeptidase

Carboxypeptidase

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Carboxypeptidases are proteolytic enzymes that perform many diverse physiological functions by removing C-terminal amino acids from proteins and peptides. Carboxypeptidases are involved in a wide range of physiological processes. For example, some carboxypeptidases function in the degradation of proteins in the digestive tract while other enzymes play biosynthetic roles in the formation of neuropeptides and peptide hormones. Based on the active site mechanism, Carboxypeptidases can be classified as metallo carboxypeptidase, serine carboxypeptidases and cysteine carboxypeptidase.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70548
    PSMA Protein, Human (HEK293, His, solution)

    Glutamate carboxypeptidase 2; FGCP; GCPII; mGCP; NAALADase I; PSMA; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1

    		Human HEK293
    PSMA protein, with a preference for tri-alpha-glutamate peptides, acts as a folate hydrolase and NAALADase enzyme. It uptakes folate in the intestines, modulates excitatory neurotransmission by hydrolyzing NAAG to release glutamate in the brain, and exhibits dipeptidyl-peptidase IV type activity by cleaving Gly-Pro-AMC in vitro. PSMA Protein, Human (HEK293, His, solution) is the recombinant human-derived PSMA protein, expressed by HEK293 , with N-6*His labeled tag.
  • HY-P72868
    Carboxypeptidase A1/CPA1 Protein, Mouse (HEK293, His)

    Carboxypeptidase A1; Cpa1

    		Mouse HEK293
    Carboxypeptidase A1 (CPA1) is an enzyme responsible for catalyzing the release of a C-terminal amino acid; however, it exhibits limited or no activity with residues such as -Asp, -Glu, -Arg, -Lys, or -Pro. This specificity in substrate recognition underscores its role as a carboxypeptidase with selectivity towards certain amino acid sequences at the C-terminus of peptides. Carboxypeptidase A1/CPA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase A1/CPA1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P76703
    PSMA Protein, Human (Biotinylated, HEK293, His)

    Glutamate carboxypeptidase 2; FGCP; GCPII; mGCP; NAALADase I; PSMA; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1

    		Human HEK293
    PSMA protein, with a preference for tri-alpha-glutamate peptides, acts as a folate hydrolase and NAALADase enzyme. It uptakes folate in the intestines, modulates excitatory neurotransmission by hydrolyzing NAAG to release glutamate in the brain, and exhibits dipeptidyl-peptidase IV type activity by cleaving Gly-Pro-AMC in vitro. PSMA Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived PSMA protein, expressed by HEK293 , with N-6*His labeled tag.
  • HY-P7745
    Cathepsin A Protein, Human (HEK293, His, solution)

    rHuCathepsin A, His; Lysosomal protective protein; CTSA; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A

    		Human HEK293
    Cathepsin A Protein, Human (HEK293, His, solution) is a 58-60 kDa human cathepsin A protein with a His-flag. Cathepsin A is a multicatalytic enzyme with carboxypeptidase activities.
  • HY-P7745A
    Cathepsin A Protein, Human (HEK293, His)

    Lysosomal protective protein; CTSA; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A

    		Human HEK293
    Cathepsin A protein is an important protective factor for β-galactosidase and neuraminidase, maintaining their stability and optimizing enzyme activity. Its carboxypeptidase activity expands its functional repertoire and can deamid tachykinins and participate in a variety of biochemical processes. Cathepsin A Protein, Human (HEK293, His) is the recombinant human-derived Cathepsin A, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P70548A
    PSMA Protein, Human (HEK293, N-His)

    Glutamate carboxypeptidase 2; FGCP; GCPII; mGCP; NAALADase I; PSMA; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1

    		Human HEK293
    PSMA protein, with a preference for tri-alpha-glutamate peptides, acts as a folate hydrolase and NAALADase enzyme. It uptakes folate in the intestines, modulates excitatory neurotransmission by hydrolyzing NAAG to release glutamate in the brain, and exhibits dipeptidyl-peptidase IV type activity by cleaving Gly-Pro-AMC in vitro. PSMA Protein, Human (HEK293, N-His) is the recombinant human-derived PSMA protein, expressed by HEK293 , with N-6*His labeled tag.
  • HY-P72869
    Carboxypeptidase B1/CPB1 Protein, Mouse (HEK293, His)

    carboxypeptidase B1; Cpb1

    		Mouse HEK293
    Carboxypeptidase B1/CPB1 protein is part of the PDGF/VEGF growth factor family and has the same structural and functional characteristics as proteins that affect cell growth, proliferation and angiogenesis. This family is critical for mediating endothelial cell responses and promoting blood vessel formation, including VEGF-C, which is involved in lymphangiogenesis. Carboxypeptidase B1/CPB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase B1/CPB1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P7732
    Carboxypeptidase A1/CPA1 Protein, Human (HEK293, His)

    rHuCarboxypeptidase A1, His; Carboxypeptidase A1; CPA1; CPA

    		Human HEK293
    Carboxypeptidase A1/CPA1 Protein, Human (HEK293, His) is an approximately 44.0 kDa human carboxypeptidase A1 protein with a His-Flag.
  • HY-P7734
    Carboxypeptidase B1/CPB1 Protein, Human (HEK293, His)

    rHuCarboxypeptidase B1, His; Carboxypeptidase B; Pancreas-Specific Protein; PASP; CPB1; CPB; PCPB

    		Human HEK293
    Carboxypeptidase B1/CPB1 Protein, Human (HEK293, His) is an approximately 47.0 kDa carboxypeptidase B1 protein with a C-terminal His-flag.
  • HY-P7736
    Carboxypeptidase E/CPE Protein, Human (HEK293 His)

    rHuCarboxypeptidase E, His; Carboxypeptidase H; Enkephalin convertase; Prohormone-processing carboxypeptidase

    		Human HEK293
    Carboxypeptidase E Protein, Human (HEK293 His) is an approximately 57.0 kDa Carboxypeptidase E protein with His-flag, expressed in HEK293-cell system.
  • HY-P7737
    Carboxypeptidase M/CPM Protein, Human (HEK293, His)

    rHuCarboxypeptidase M, His; Carboxypeptidase M; CPM

    		Human HEK293
    Carboxypeptidase M Protein, Human (HEK293, His) is an approximately 55.0 kDa Carboxypeptidase M protein with a His-flag. Carboxypeptidase M is a membrane-bound arginine/lysine carboxypeptidase enzyme belongs to the carboxypeptidases family.
  • HY-P71200
    PGCP Protein, Mouse (HEK293, His)

    PGCP; Carboxypeptidase Q; Hematopoietic lineage switch 2; Plasma glutamate carboxypeptidase; Cpq; Hls2

    		Mouse HEK293
    PGCP is a carboxypeptidase with a potentially critical role in the hydrolysis of circulating peptides. It catalyzes the cleavage of terminally unsubstituted dipeptides, releasing amino acids. PGCP Protein, Mouse (HEK293, His) is the recombinant mouse-derived PGCP protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P71240
    PSMA Protein, Mouse (HEK293, His)

    Glutamate carboxypeptidase 2; FGCP; GCPII; mGCP; NAALADase I; PSMA; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1

    		Mouse HEK293
    PSMA Protein, a multifunctional enzyme, acts as a folate hydrolase and NAALADase with a preference for tri-alpha-glutamate peptides. In the intestine, it aids folate uptake for metabolic processes. In the brain, PSMA modulates neurotransmission by hydrolyzing NAAG, releasing glutamate. It also shows dipeptidyl-peptidase IV type activity and effectively cleaves Gly-Pro-AMC, highlighting its versatile enzymatic functions. PSMA Protein, Mouse (HEK293, His) is the recombinant mouse-derived PSMA protein, expressed by HEK293 , with N-6*His labeled tag.
  • HY-P73674
    RISC Protein, Mouse (HEK293, His)

    Retinoid-inducible serine carboxypeptidase; SCPEP1; RISC; SCP1

    		Mouse HEK293
    RISC proteins have emerged as potential regulators of blood vessel wall and renal homeostasis, suggesting a possible role for RISC proteins in regulating key processes in these physiological environments. RISC Protein, Mouse (HEK293, His) is the recombinant mouse-derived RISC protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P73675
    RISC Protein, Human (HEK293, His)

    Retinoid-inducible serine carboxypeptidase; SCPEP1; RISC; SCP1

    		Human HEK293
    RISC protein is intricately linked to maintaining homeostasis in the vascular wall and kidney, implying a regulatory role in physiological processes. Its potential involvement underscores its importance in sustaining balance and optimal functioning in these systems. Further exploration of RISC protein mechanisms holds promise for insights contributing to therapeutic potential in vascular and renal health. RISC Protein, Human (HEK293, His) is the recombinant human-derived RISC protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74346
    Cathepsin A Protein, Mouse (HEK293, His)

    Lysosomal protective protein; CTSA; Cathepsin A; PPCA; Ppgb

    		Mouse HEK293
    Cathepsin A, a multifunctional protein, crucially supports beta-galactosidase and neuraminidase activities.It forms protective associations with these enzymes, ensuring their stability and overall function.Cathepsin A also displays carboxypeptidase activity and the ability to deamidate tachykinins, highlighting its diverse enzymatic functions.Cathepsin A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cathepsin A protein, expressed by HEK293 , with C-10*His labeled tag.
  • HY-P75449
    Carboxypeptidase B2/CPB2 Protein, Rat (HEK293, His)

    Carboxypeptidase B2; CPU; pCPB; TAFI; CPB2

    		Rat HEK293
    Carboxypeptidase B2 (CPB2) protein acts as an enzyme that cleaves C-terminal arginine or lysine residues from biologically active peptides, including kinins or anaphylatoxins circulating in the blood, thereby regulating their activity. Furthermore, CPB2 plays a key role in downregulating fibrinolysis by removing C-terminal lysine residues from fibrin that has been partially degraded by plasmin. Carboxypeptidase B2/CPB2 Protein, Rat (HEK293, His) is the recombinant rat-derived Carboxypeptidase B2/CPB2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75450
    Carboxypeptidase B2/CPB2 Protein, Mouse (HEK293, His)

    Carboxypeptidase B2; CPU; pCPB; TAFI; CPB2

    		Mouse HEK293
    Carboxypeptidase B2/CPB2 protein cleaves C-terminal arginine or lysine residues from active peptides, regulating their activities. It also down-regulates fibrinolysis by removing C-terminal lysine residues from degraded fibrin. CPB2 contributes to peptide signaling and fibrinolysis regulation. Carboxypeptidase B2/CPB2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase B2/CPB2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75452
    Carboxypeptidase A2/CPA2 Protein, Rat (HEK293, His)

    Carboxypeptidase A2; CPA2

    		Rat HEK293
    Carboxypeptidase A2/CPA2 protein is a member of the key peptidase M14 family, which plays an important role in peptide hydrolysis and contributes to the regulation of biological pathways. CPA2 may share conserved features with related proteins. Carboxypeptidase A2/CPA2 Protein, Rat (HEK293, His) is the recombinant rat-derived Carboxypeptidase A2/CPA2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75988
    PSMA3 Protein, Human (His)

    Proteasome subunit alpha type-3; Macropain subunit C8; PSMA3; HC8; PSC8

    		Human E. coli
    PSMA3 is a protein involved in protein degradation. PSMA3 Protein, Human (His) is the recombinant human-derived PSMA3 protein, expressed by E. coli , with N-His labeled tag.
Cat. No. Product Name Effect Purity