1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Lyases (EC 4)

Enzymes can be classified systematically according to the difference between reaction and substrate specificity, and the mechanism of action. Lyases (EC 4.x.x.x) are a group of enzymes that catalyze the cleavage of C-C, C-O, C-N and other bonds by methods other than hydrolysis and oxidation, or conversely add a group to a double bond. Lyases differ from other enzymes in that they require only one substrate for the reaction in one direction, which differs from other enzymes, but two substrates for the reverse reaction. Common lyases include decarboxylases, aldolases and dehydratases, etc. Lyases can be further classified into seven subclasses. Lyases in EC 4.1 cleave carbon-carbon bonds;EC 4.2 of lyases that break carbon-oxygen bonds;EC 4.3 of lyases cleave carbon-nitrogen bonds; Lyases in EC 4.1 split carbon-sulfur bonds; Lyases in EC 4.5 cleave carbon-halide bonds; Lyases in EC 4.5 fracture phosphorus-oxygen bonds; EC 4.99 includes other lyases.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7718
    Carbonic Anhydrase 1 Protein, Human (His)

    rHuCarbonic Anhydrase 1, His; Carbonic Anhydrase 1; Carbonate Dehydratase I; Carbonic Anhydrase B; CAB; Carbonic Anhydrase I; CA1

    Human E. coli
    Carbonic Anhydrase 1 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Carbonic Anhydrase 1 (CA1) expression and CA1-mediated calcification are significantly associated with atherosclerosis (AS) progression.
  • HY-P72862
    Carbonic Anhydrase 4 Protein, Human (HEK293, His)

    Carbonic anhydrase 4; Carbonate dehydratase IV; CA-IV; CA4

    Human HEK293
    Carbonic anhydrase 4 catalyzes the reversible hydration of carbon dioxide and plays a crucial role in maintaining intracellular and extracellular pH. Carbonic Anhydrase 4 Protein, Human (HEK293, His) is the recombinant human-derived Carbonic Anhydrase 4 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 4 Protein, Human (HEK293, His) is 265 a.a., with molecular weight of ~30 kDa.
  • HY-P70810
    Carbonic Anhydrase 14 Protein, Mouse (275a.a, HEK293, His)

    Carbonic Anhydrase 14; Carbonate Dehydratase XIV; Carbonic Anhydrase XIV; CA-XIV; CA14;

    Mouse HEK293
    The carbonic anhydrase 14 (CA14) protein catalyzes the reversible hydration of carbon dioxide, converting it into bicarbonate ions and protons. Its enzymatic activity is essential for physiological processes, regulating pH and maintaining acid-base balance. Carbonic Anhydrase 14 Protein, Mouse (275a.a, HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 14 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Carbonic Anhydrase 14 Protein, Mouse (275a.a, HEK293, His) is 275 a.a., with molecular weight of 41-50 kDa.
  • HY-P72863
    Carbonic Anhydrase 9 Protein, Human (HEK293, Fc)

    Carbonic anhydrase 9; CA-IX; P54/58N; pMW1; CA9; G250; MN

    Human HEK293
    The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (HEK293, Fc) is 377 a.a., with molecular weight of ~67.4 kDa.
  • HY-P72866
    CA12/Carbonic Anhydrase 12 Protein, Human (HEK293, His)

    Carbonic anhydrase 12; Carbonate dehydratase XII; CA-XII; CA12

    Human HEK293
    CA12 (or carbonic anhydrase 12) plays a crucial role in the reversible hydration of carbon dioxide, catalyzing its conversion into bicarbonate ions and protons. This enzymatic activity is essential for key physiological processes, including regulating pH and maintaining acid-base balance. CA12/Carbonic Anhydrase 12 Protein, Human (HEK293, His) is the recombinant human-derived CA12/Carbonic Anhydrase 12 protein, expressed by HEK293 , with C-His labeled tag. The total length of CA12/Carbonic Anhydrase 12 Protein, Human (HEK293, His) is 267 a.a., with molecular weight of 40-45 kDa.
  • HY-P72348
    Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His)

    CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250

    Human HEK293
    The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (Biotinylated, HEK293, Avi-His) is 377 a.a., with molecular weight of ~60 kDa.
  • HY-P70064
    Carbonic Anhydrase 9 Protein, Human (HEK293, His)

    rHuCarbonic Anhydrase 9/CA9, His; CA9; CA-IX; Carbonic Anhydrase IX; Carbonate dehydratase IX; G250; MN; P54/58N; RCC; RCC-associated protein G250

    Human HEK293
    The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Human (HEK293, His) is 377 a.a., with molecular weight of 45-60 kDa.
  • HY-P72860
    Carbonic Anhydrase 2 Protein, Human (C-His, Solution)

    Carbonic anhydrase 2; Carbonic anhydrase C; CAC; CA-II; CA2

    Human E. coli
    Carbonic Anhydrase 2 (CA2) catalyzes the reversible hydration of carbon dioxide. Mutations in CA2 are linked to osteopetrosis and renal tubular acidosis. The gene exhibits biased expression in various tissues, notably in the stomach and colon. Two transcript variants, encoding different isoforms, have been identified. Carbonic Anhydrase 2 Protein, Human (C-His, Solution) is the recombinant human-derived Carbonic Anhydrase 2 protein, expressed by E. coli , with C-His labeled tag. The total length of Carbonic Anhydrase 2 Protein, Human (C-His, Solution) is 259 a.a., with molecular weight of ~30 kDa.
  • HY-P77944
    GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi)

    Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL

    Human HEK293
    GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi) is 407 a.a., with molecular weight of 55-65 kDa.
  • HY-P72861
    Carbonic Anhydrase 2 Protein, Mouse (His)

    Carbonic anhydrase 2; Carbonic anhydrase C; CAC; CA-II; CA2

    Mouse HEK293
    Carbonic Anhydrase 2 Protein is a member of the carbonic anhydrase isozyme family, responsible for catalyzing the reversible hydration of carbon dioxide. Mutations in CA2 are linked to osteopetrosis and renal tubular acidosis. The gene exhibits biased expression in various tissues, notably in the stomach and colon. CA2 plays vital role in the regulation of ion transport and pH balance and is involved in many biological processes. Carbonic Anhydrase 2 Protein, Mouse (His) is the recombinant mouse-derived Carbonic Anhydrase 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 2 Protein, Mouse (His) is 259 a.a., with molecular weight of 30-35 kDa.
  • HY-P73062
    Fumarate Hydratase/FH Protein, Human (His)

    Fumarate Hydratase; Fumarase; HsFH; FH

    Human E. coli
    The fumarate hydratase/FH protein plays a key role in cellular processes as it catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle, which is essential for energy production through the production of NADH . Fumarate Hydratase/FH Protein, Human (His) is the recombinant human-derived Fumarate Hydratase/FH protein, expressed by E. coli , with C-His labeled tag. The total length of Fumarate Hydratase/FH Protein, Human (His) is 466 a.a., with molecular weight of ~50 kDa.
  • HY-P76753
    CA5A Protein, Human (His-Met)

    Carbonic anhydrase 5A, mitochondrial; Carbonic anhydrase VA; CA-VA; CA5

    Human E. coli
    CA5A protein is a mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3, providing essential bicarbonate for mitochondrial enzymes. Impermeable mitochondria rely on CA5A to support enzymatic reactions critical to intermediary metabolism, including the urea cycle and the Krebs cycle. CA5A Protein, Human (His-Met) is the recombinant human-derived CA5A protein, expressed by E. coli , with N-Met, C-His labeled tag. The total length of CA5A Protein, Human (His-Met) is 266 a.a., with molecular weight of ~33 kDa.
  • HY-P7720
    Carbonic Anhydrase 4 Protein, Human (His)

    rHuCarbonic Anhydrase 4, His; Carbonic Anhydrase 4; Carbonate Dehydratase IV; Carbonic Anhydrase IV; CA4

    Human E. coli
    Carbonic Anhydrase 4 Protein, Human (His) a recombinant Mouse Carbonic Anhydrase 4 produced in E. coli, has a His tag at the N-terminus. The Carbonic Anhydrase 4 (CA4) protein is a zinc metalloenzyme that catalyzes the reversible hydration and dehydration of CO2 and HCO3-.
  • HY-P7722
    Carbonic Anhydrase 7 Protein, Human (His)

    rHuCarbonic Anhydrase 7, His; Carbonic Anhydrase 7; Carbonate Dehydratase VII; Carbonic Anhydrase VII; CA7

    Human E. coli
    Carbonic Anhydrase VII/CA7 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Human carbonic anhydrase VII (hCA VII) is a cytosolic isoform belonging to the α-CA family that shows high carbon dioxide hydration activity.
  • HY-P7723
    Carbonic Anhydrase 8 Protein, Human (His)

    rHuCarbonic Anhydrase 8, His; Carbonic Anhydrase-Related Protein; CARP; Carbonic Anhydrase VIII; CA8; CALS

    Human E. coli
    Carbonic Anhydrase VIII/CA8 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Carbonic anhydrase 8 (CA8), an isozyme of α-carbonic anhydrases (CAs), is an allosteric inhibitor of inositol trisphosphate receptor-1 (ITPR1), which regulates neuronal intracellular calcium release.
  • HY-P7726
    Carbonic Anhydrase 13 Protein, Human (His)

    rHuCarbonic Anhydrase 13, His; Carbonic Anhydrase 13; Carbonate Dehydratase XIII; Carbonic Anhydrase XIII; CA13

    Human E. coli
    Carbonic Anhydrase 13 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Human Carbonic Anhydrase 13, a member of the human carbonic anhydrase (hCA), can control pH and ion balance regulation.
  • HY-P7729
    Carbonic Anhydrase 11 Protein, Human (HEK293, His)

    rHuCarbonic Anhydrase 11, His; Carbonic Anhydrase-Related Protein 11; CARP XI; Carbonic Anhydrase-Related Protein 2; CA-RP II; CA11; CARP2

    Human HEK293
    Carbonic Anhydrase 11 Protein, Human (HEK293, His) is an approximately 38.0 kDa carbonic anhydrase 11 protein with a His-flag. Carbonic anhydrases (CAs) are found in many organisms, in which they contribute to several important biological processes.
  • HY-P7883
    DNA polymerase beta Protein, Human (His)

    rHuDNA polymerase beta, His; DNA Polymerase Beta; POLB

    Human E. coli
    DNA polymerase beta Protein, Human (His), a DNA repair enzyme, is involved in various types of DNA repair. DNA polymerase beta Protein performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance.
  • HY-P700882
    Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His)

    CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC

    Cynomolgus HEK293
    Carbonic Anhydrase 9 Protein catalyzes the reversible hydration of carbon dioxide, essential for converting it to bicarbonate ions and protons, and vice versa. This enzymatic activity is crucial in physiological processes like acid-base balance regulation, respiration, and cellular pH homeostasis. Carbonic Anhydrase 9 Protein is vital for carbon dioxide transport and metabolism, contributing to overall regulation of its levels in the body. Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) is 365 a.a., with molecular weight of 50-60 kDa.
  • HY-P7478
    Aldolase C Protein, Human (HEK293, His)

    rHuFructose-bisphosphate aldolase C, His; ALDOC; Fructose-bisphosphate aldolase C

    Human HEK293
    Aldolase C Protein, Human (HEK293, His) is a recombinant human Fructose-bisphosphate aldolase C produced in HEK293 cells, with a His tag at the C-terminus. Aldolase C (ALDOC), which belongs to the aldolase family, is found in normal brain tissue and is responsible for the repair of injured tissue.
Cat. No. Product Name Effect Purity