1. Recombinant Proteins
  2. Complement System
  3. Complement Component 5
Cat. No. Product Name / Synonyms Species Source
  • HY-P700862
    Complement C5/C5a Protein, Human (HEK293, His)

    Complement C5; C5; CPAMD4; ECLZB; C5a; C5b; C5D

    Human HEK293
    Activated by a C5 convertase, Complement C5 induces the assembly of C5-C9, forming the membrane attack complex. The transient C6 binding site on C5b is pivotal for lytic complex formation. C5 proteolytic degradation yields C5a anaphylatoxin, a local inflammatory mediator. Interacting with C5AR1, C5a induces diverse responses, including calcium release, muscle contraction, vascular permeability, and histamine release. As a potent chemokine, C5a guides leukocyte migration to inflammation sites, orchestrating immune responses. Complement C5/C5a Protein, Human (HEK293, His) is the recombinant human-derived Complement C5/C5a protein, expressed by HEK293, with C-His labeled tag. The total length of Complement C5/C5a Protein, Human (HEK293, His) is 1658 a.a., with molecular weight of 110-114 kDa (α chain) & 69-73 kDa (β chain), respectively.
  • HY-P7864
    Complement C5/C5a Protein, Human

    rHuComplement C5/C5a; Complement C5; C5a anaphylatoxin; C5a

    Human E. coli
    Complement C5/C5a Protein, Human is a recombinant human complement C5a. C5a is a 74-amino acid glycoprotein generated on activation of the C system. Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling.
  • HY-P7695
    Complement C5/C5a Protein, Mouse

    rMuC5a; Complement C5; Hemolytic Complement; C5a

    Mouse E. coli
    Complement C5/C5a Protein, Mouse is a recombinant mouse complement component 5a (C5a). C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response.
  • HY-P77540
    Complement C5/C5a Protein, Mouse (Biotinylated)

    Complement C5; Hemolytic Complement; C5a

    Mouse E. coli
    Complement C5/C5a Protein activates late complement components to form the membrane attack complex, C5-C9. C5b binds C6, initiating lytic complex assembly. C5a, produced by C5 degradation, acts as an anaphylatoxin, inducing local inflammation. C5a stimulates intracellular calcium release, smooth muscle contraction, vascular permeability, histamine release, and acts as a chemokine, guiding leukocyte migration. Complement C5/C5a Protein, Mouse (Biotinylated) is the recombinant mouse-derived Complement C5/C5a protein, expressed by E. coli, with tag free. The total length of Complement C5/C5a Protein, Mouse (Biotinylated) is 77 a.a., with molecular weight of ~9 KDa.
  • HY-P71719
    Complement C5/C5a Protein, Pig (P.pastoris, His)

    C5; Complement C5a anaphylatoxin

    Pig P. pastoris
    Complement C5/C5a Protein, a component of the complement system, is involved in the immune response and inflammation. It is cleaved to generate C5a, a potent pro-inflammatory mediator. Complement C5/C5a Protein's role in immune regulation and its potential as a therapeutic target make it a promising candidate for the treatment of inflammatory disorders and autoimmune diseases. Complement C5/C5a Protein, Pig (P.pastoris, His) is the recombinant pig-derived Complement C5/C5a protein, expressed by P. pastoris , with N-His labeled tag. The total length of Complement C5/C5a Protein, Pig (P.pastoris, His) is 74 a.a., with molecular weight of ~10.6 kDa.
  • HY-P700959
    Complement C5/C5a Protein, Human (His)

    C5a; Complement C5; C5; CPAMD4; ECLZB

    Human E. coli
    Complement C5 is activated by C5 convertase, inducing C5-C9 assembly to form the membrane attack complex. The transient C6 binding site on C5b is critical for the formation of the cleavage complex. Complement C5/C5a Protein, Human (His) is the recombinant human-derived Complement C5/C5a protein, expressed by E. coli , with N-His labeled tag. The total length of Complement C5/C5a Protein, Human (His) is 74 a.a., with molecular weight of 13-14 kDa.
Cat. No. Product Name Effect Purity