Steroids

A steroid is an organic compound with four rings arranged in a specific molecular configuration, composed of seventeen carbon atoms, bonded in four "fused" rings: three six-member cyclohexane rings (rings A, B and C) and one five-member cyclopentane ring (the D ring). Hundreds of steroids are found in plants, animals and fungi. Examples include the dietary lipid cholesterol, the sex hormones estradiol and testosterone. Steroids have two principal biological functions: certain steroids (such as cholesterol) are important components of cell membranes which alter membrane fluidity, and many steroids are signaling molecules which activate steroid hormone receptors.

Cardiacglycosides (16)

Steroids (370):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-N0583

Hydrocortisone 50-23-7 99.90%

Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

Hydrocortisone	50-23-7	99.90%
Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

HY-B0141

Estradiol	50-28-2	99.99%
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering.

HY-N4000

Digitonin	11024-24-1
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth. Digitonin is an natural detergent.

HY-B1618

Corticosterone	50-22-6	99.70%
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect.

HY-N0322

Cholesterol	57-88-5	98.53%
Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

HY-N0437R

Progesterone (Standard)	57-83-0
Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-N11465

(25R)-Spirost-4-ene-3,6,12-trione 214681-62-6

(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L.
HY-117484

Rubrosterone 19466-41-2

Rubrosterone is a metabolite of insect metamorphosing substances, that can be isolated from Achyranthes rubrofuca and A. fmaiei (Amaranthaceae).

(25R)-Spirost-4-ene-3,6,12-trione	214681-62-6
(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L.

Rubrosterone	19466-41-2
Rubrosterone is a metabolite of insect metamorphosing substances, that can be isolated from Achyranthes rubrofuca and A. fmaiei (Amaranthaceae).

HY-19696

Tauroursodeoxycholate	14605-22-2	99.13%
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-N0437

Progesterone 57-83-0 99.42%

Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
HY-76847

Chenodeoxycholic Acid 474-25-9 ≥98.0%

Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

Progesterone	57-83-0	99.42%
Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

Chenodeoxycholic Acid	474-25-9	≥98.0%
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

HY-113134

25-Hydroxycholesterol	2140-46-7	≥98.0%
25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC₅₀≈65 nM) and selective suppressor of IgA production by B cells.

HY-N0171A

Beta-Sitosterol (purity>98%)	83-46-5	≥98.0%
Beta-Sitosterol (purity>98%) is a plant sterol. Beta-Sitosterol (purity>98%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

HY-17024

Cyclopamine 4449-51-8 99.97%

Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC₅₀ of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
HY-B0542

Ouabain Octahydrate 11018-89-6 99.96%

Ouabain Octahydrate is an inhibitor of Na⁺/K⁺-ATPase, used for the treatment of congestive heart failure.
HY-N0593

Deoxycholic acid 83-44-3 99.82%

Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.
HY-B0469

Medroxyprogesterone acetate 71-58-9 99.88%

Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.
HY-B0172

Lithocholic acid 434-13-9 ≥98.0%

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.

Cyclopamine	4449-51-8	99.97%
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC₅₀ of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.

Ouabain Octahydrate	11018-89-6	99.96%
Ouabain Octahydrate is an inhibitor of Na⁺/K⁺-ATPase, used for the treatment of congestive heart failure.

Deoxycholic acid	83-44-3	99.82%
Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.

Medroxyprogesterone acetate	71-58-9	99.88%
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.

Lithocholic acid	434-13-9	≥98.0%
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.

HY-17463

Prednisolone	50-24-8	99.96%
Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research.

HY-B1788

Taurocholic acid 81-24-3 99.18%

Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

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