2. Productos naturales
  3. Steroids
  4. Cardiacglycosides

Cardiacglycosides

Cardiacglycosides (87):

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-B1030
    Lanatoside C 17575-22-3 99.88%
    Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71.
    Lanatoside C
  • HY-A0154
    Deslanoside 17598-65-1 99.79%
    Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
    Deslanoside
  • HY-N2453
    Convallatoxin 508-75-8 99.72%
    Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties.
    Convallatoxin
  • HY-N4252
    Periplocymarin 32476-67-8 99.90%
    Periplocymarin, a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound.
    Periplocymarin
  • HY-N8441
    Neriifolin 466-07-9 99.70%
    Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
    Neriifolin
  • HY-N16733
    Deacetyltanghinin 4589-95-1
    Deacetyltanghinin is a selective inhibitor targeting Na+/K+ ATPase, acting through non-covalent binding but is highly cardiotoxic. Deacetyltanghinin inhibits Na+/K+ ATPase activity, induces cancer cell apoptosis (involving caspase pathway activation), and at the same time affect the TXA2-PGI2 balance in the rabbit heart. Deacetyltanghinin has significant anti-cancer activity and is mainly used in the research field of targeted therapy of malignant tumors such as breast cancer and lung cancer. At the same time, attention should be paid to the regulation of its cardiotoxicity.
    Deacetyltanghinin
  • HY-111934
    Cymarin 508-77-0
    Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant.
    Cymarin
  • HY-N8549A
    5-Dihydrocortisone 28423-48-5 99.83%
    5-Dihydrocortisone is a 5-Dihydrocortisone with mixture of isomers. 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver
    5-Dihydrocortisone
  • HY-N1156
    Thevetin B 27127-79-3 98.71%
    Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana.
    Thevetin B
  • HY-N12520
    Helveticoside 630-64-8
    Helveticoside (Strophanthidin-digitoxoside) is a helveticosid, possesses an ED50 of 0.17 μM for isolated guinea-pig ileum. Helveticoside has anticancer effect.
    Helveticoside
  • HY-N10303
    Withangulatin A 120824-03-5 99.76%
    Withangulatin A is the inhibitor for COX-2. Withangulatin A inhibits MAPK, NF-κB, Akt/mTOR/p70S6K pathway, exhibits antitumor, anti-inflammatory and trypanocidal activities.
    Withangulatin A
  • HY-N12188
    Stigmasta-3,5-dien-7-one 2034-72-2 99.84%
    Stigmasta-3,5-dien-7-one is a steroid compound that can be isolated from Harrisonia abyssinica. Stigmasta-3,5-dien-7-one blocks the NF-κB signaling pathway via down-regulation of phospho-p38 mitogen-activated protein kinase and phosphorylation and degradation of inhibitor of NF-κB α. Stigmasta-3,5-dien-7-one reduces LPS (HY-D1056)-induced nitric oxide, PGE2, and pro-inflammatory cytokine levels in macrophages. Stigmasta-3,5-dien-7-one can be used for inflammation diseases.
    Stigmasta-3,5-dien-7-one
  • HY-W671746
    Thevetin A 37933-66-7 98.95%
    Thevetin A is a thevetia cardiac glycoside. Thevetin A can be isolated from the methanol extract of the seeds of Cascabela thevetioides.
    Thevetin A
  • HY-N3672
    Cynatratoside A 97399-96-7 99.62%
    Cynatratoside A, an oligoglycoside, is a nature product that could be isolated from the roots of Cynanchum paniculatum.
    Cynatratoside A
  • HY-16022
    Acetyldigitoxin 1111-39-3
    Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch.
    Acetyldigitoxin
  • HY-N12799
    Digitalin 752-61-4 98.89%
    Digitalin (Digitalinum verum) is a cardiac glycoside and can be isolated from Digitalis.
    Digitalin
  • HY-N11690
    Oleandrigenin 465-15-6 98.42%
    Oleandrigenin is a potent cardiotonic steroid. Oleandrigenin shows Na+/K+-ATP-ase inhibiting and cytotoxic activities.
    Oleandrigenin
  • HY-N7669
    Taccalonolide C 117803-96-0 99.13%
    Taccalonolides C is an anti-cancer agent.
    Taccalonolide C
  • HY-123075
    Odoroside H 18810-25-8 98%
    Odoroside H is a natural cardenolide with anticancer activities.
    Odoroside H
  • HY-N12143
    Acetylthevetin A 1356494-03-5 99.20%
    Acetylthevetin A is a natural product isolated from oleander (Cascabela thevetioides).
    Acetylthevetin A