1. Natural Products
  2. Steroids
  3. Cardiacglycosides

Cardiacglycosides

Cardiacglycosides (29):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1030
    Lanatoside C 17575-22-3 99.83%
    Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71.
    Lanatoside C
  • HY-N8441
    Neriifolin 466-07-9 99.43%
    Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
    Neriifolin
  • HY-N4252
    Periplocymarin 32476-67-8 ≥99.0%
    Periplocymarin, a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound.
    Periplocymarin
  • HY-N0817
    Polyphyllin G 76296-75-8
    Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs). Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy.
    Polyphyllin G
  • HY-16022
    Acetyldigitoxin 1111-39-3
    Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch.
    Acetyldigitoxin
  • HY-N7669
    Taccalonolide C 117803-96-0 99.13%
    Taccalonolides C is an anti-cancer agent.
    Taccalonolide C
  • HY-N1213
    Sprengerinin C 88861-91-0
    Sprengerinin is a potential angiogenesis inhibitor. Sprengerinin exerts anti-tumorigenic effects in vitro.
    Sprengerinin C
  • HY-111934
    Cymarin 508-77-0
    Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant.
    Cymarin
  • HY-N5093
    Glucodigifucoside 2446-63-1
    Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN.
    Glucodigifucoside
  • HY-N6575
    7β-Hydroxybufalin 20143-97-9
    7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase.
    7β-Hydroxybufalin
  • HY-N3672
    Cynatratoside A 97399-96-7
    Cynatratoside A, an oligoglycoside, is a nature product that could be isolated from the roots of Cynanchum paniculatum.
    Cynatratoside A
  • HY-N10023
    Physalin O 120849-18-5
    Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities.
    Physalin O
  • HY-N8270
    Physalin H 70241-09-7
    Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively.
    Physalin H
  • HY-N8679
    Physalin C 27503-33-9
    Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells.
    Physalin C
  • HY-N10303
    Withangulatin A 120824-03-5
    Withangulatin A is a selective cyclooxygenase-2 (COX-2) inhibitor. Withangulatin A can be isolated from Physalis angulata L. Withangulatin A has anti-tumor, trypanocidal activity and anti-inflammatory function.
    Withangulatin A
  • HY-N7328
    Lanatoside B 17575-21-2
    Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata.
    Lanatoside B
  • HY-123075
    Odoroside H 18810-25-8
    Odoroside H is a natural cardenolide with anticancer activities.
    Odoroside H
  • HY-N10040
    Poststerone 10162-99-9
    Poststerone is a nature product. Poststerone is a metabolite of insect metamorphosing substances from Cyathula capata.
    Poststerone
  • HY-N12430
    Marsdenoside A 858360-56-2
    Marsdenoside A (compound 7) is a Marsdenoside isolated from Alocasia genus. Marsdenoside A has a weak growth inhibitory effect on two tumor cell lines, MGC-803 and HT-29, with IC50 >50 μg/mL.
    Marsdenoside A
  • HY-N12437
    Marsdenoside B 858360-57-3
    Marsdenoside B (compound 8) is a Marsdenoside isolated from Alocasia genus. Marsdenoside B inhibits the growth of tumor cell lines MGC-803 and HT-29 with IC50s of 25.6 μg/mL and 32.4 μg/mL, respectively.
    Marsdenoside B