Taccalonolide C
Based on 1 Customer Validation
Taccalonolides C is an anti-cancer agent.
For research use only. We do not sell to patients.
- Purity: 99.13%
- CAS No.: 117803-96-0
- Formula: C36H46O14
- Molecular Weight:702.74
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 117803-96-0
-
Appearance Solid
-
Molecular Weight 702.74
-
Formula C36H46O14
-
Color White to off-white
-
SMILES
C[C@]1([C@H]2OC(C)=O)[C@]([C@](OC3=O)([H])[C@]([C@]4([C@](O)3C)C)([H])[C@]1([H])[C@@H](CC4=O)C)([H])[C@@]([C@H](C5=O)OC(C)=O)([H])[C@]([C@@]6([C@]5([H])C[C@@]7([H])[C@@](O7)([H])[C@@H]6OC(C)=O)C)([H])[C@@H]2OC(C)=O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (142.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (3.56 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (283 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4230 mL | 7.1150 mL | 14.2300 mL | 35.5750 mL |
| 5 mM | 0.2846 mL | 1.4230 mL | 2.8460 mL | 7.1150 mL | |
| 10 mM | 0.1423 mL | 0.7115 mL | 1.4230 mL | 3.5575 mL | |
| 15 mM | 0.0949 mL | 0.4743 mL | 0.9487 mL | 2.3717 mL | |
| 20 mM | 0.0712 mL | 0.3558 mL | 0.7115 mL | 1.7788 mL | |
| 25 mM | 0.0569 mL | 0.2846 mL | 0.5692 mL | 1.4230 mL | |
| 30 mM | 0.0474 mL | 0.2372 mL | 0.4743 mL | 1.1858 mL | |
| 40 mM | 0.0356 mL | 0.1779 mL | 0.3558 mL | 0.8894 mL | |
| 50 mM | 0.0285 mL | 0.1423 mL | 0.2846 mL | 0.7115 mL | |
| 60 mM | 0.0237 mL | 0.1186 mL | 0.2372 mL | 0.5929 mL | |
| 80 mM | 0.0178 mL | 0.0889 mL | 0.1779 mL | 0.4447 mL | |
| 100 mM | 0.0142 mL | 0.0712 mL | 0.1423 mL | 0.3558 mL |
Powered by Bioz