1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. CSF & Receptors
  4. G-CSF

Granulocyte colony stimulating factor (G-CSF; CSF 3) is a pro-inflammatory cytokine which primarily stimulates the survival, proliferation, differentiation and function of neutrophil granulocyte progenitor cells and mature neutrophils. Human G-CSF is secreted mainly by monocytes and macrophages, but is also produced by endothelial cells, fibroblasts, and bone marrow stromal cells. G-CSF binds and activates its cognate receptor G-CSFR on neutrophils and their progenitors, which initiates downstream signaling cascades that include the Jak-STAT and MAP kinase pathways. G-CSF is a major regulator of neutrophil development and contributes to the regulation of multipotent hematopoietic progenitors. In addition, G-CSF also influences the phenotype and function of mature neutrophils and does so by modulating expression of for example chemokine receptors, up-regulating phagocytosis and production of reactive oxygen species (ROS) and enhancing bactericidal activity of neutrophils. It is worth mentioning that G-CSF is an FDA- and EMA- approved drug commonly used to treat neutropenia and to mobilize bone marrow hematopoietic stem cells for transplantation.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7015A
    G-CSF Protein, Human (CHO)

    rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    Human CHO
    G-CSF Protein, Human (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.
  • HY-P73073
    G-CSF Protein, Human (HEK293, Fc)

    Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33

    Human HEK293
  • HY-P73523
    G-CSF Protein, Human (HEK293)

    Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33

    Human HEK293
  • HY-P7068
    G-CSF Protein, Mouse (CHO)

    rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    Mouse CHO
    G-CSF Protein, Mouse (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.
  • HY-P7015
    G-CSF Protein, Human (167a.a)

    rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    Human E. coli
    G-CSF Protein, Human (167a.a) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.
  • HY-P70554
    G-CSF Protein, Mouse (HEK 293, His)

    Granulocyte colony-stimulating factor; Csf3; G-CSF

    Mouse HEK293
  • HY-P70422
    G-CSF Protein, Human

    Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF

    Human E. coli
    G-CSF Protein, Human is a glycoprotein, acting to stimulate granulopoiesis, the innate immunity, and the differentiation of neural progenitor cells.
  • HY-P7093A
    G-CSF Protein, Rat (HEK293)

    rRtG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    Rat HEK293
    G-CSF Protein, Rat (HEK293) is a glycoprotein, acting to stimulate granulopoiesis, the innate immunity, and the differentiation of neural progenitor cells.
  • HY-P700083AF
    Animal-Free G-CSF Protein, Human (His)

    CSF-3; MGI-1G; GM-CSF beta; pluripoietin

    Human E. coli
  • HY-P700178AF
    Animal-Free G-CSF Protein, Mouse (His)

    rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    Mouse E. coli
Cat. No. Product Name Effect Purity