2. Oligonucleotides
  3. Nucleotides and their Analogs

Nucleotides and their Analogs

Nucleotides are building blocks of nucleic acids DNA and RNA, and serve as cofactors in sugar and lipid metabolism, in polyamine biosynthesis, in methylation reactions, and as carriers of energy. They are also constituents of the redox coenzymes, NAD(P) and FAD, and of signal molecules such as (p)ppGpp, which is involved in coordinating RNA synthesis with protein synthesis. Nucleotides are composed of a nitrogenous base, a five-carbon sugar (ribose or deoxyribose), and at least one phosphate group. Thus a nucleoside plus a phosphate group yields a nucleotide. The nucleotides are either ribo- or deoxyribonucleotides, and they are found either as mono-, di-, or triphosphates. Nucleoside triphosphates (ATP, GTP, CTP and UTP), play a central role in cell metabolism.

Nucleotides and their Analogs (58):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B2176
    ATP 56-65-5 99.62%
    ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP
  • HY-F0003
    NADPH tetrasodium salt 2646-71-1 99.99%
    NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. The demand for NADPH tetrasodium salt is particularly high in proliferating cancer cells, where it acts as a cofactor for the synthesis of nucleotides, proteins, and fatty acids. NADPH tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis.
    NADPH tetrasodium salt
  • HY-12695
    Guanosine 5'-triphosphate trisodium salt 36051-31-7
    Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of signal transduction of G proteins.
    Guanosine 5'-triphosphate trisodium salt
  • HY-W010737
    Guanosine-5'-triphosphate disodium salt 56001-37-7 99.42%
    Guanosine-5'-triphosphate disodium salt (5'-GTP trisodium salt) is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
    Guanosine-5'-triphosphate disodium salt
  • HY-107372
    Uridine triphosphate 63-39-8
    Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
    Uridine triphosphate
  • HY-113400
    Cytidine diphosphate 63-38-7
    Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine diphosphate
  • HY-113066A
    Guanosine 5'-diphosphate disodium salt 7415-69-2
    Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate disodium salt can be used in the research of inflammation, such as anemia of inflammation (AI).
    Guanosine 5'-diphosphate disodium salt
  • HY-F0002A
    NADP disodium salt 24292-60-2 99.41%
    NADP disodium salt (Disodium NADP), a nicotinamide adenine dinucleotide, is a redox cofactor. NADP disodium salt is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH).
    NADP disodium salt
  • HY-125818
    Cytidine-5'-triphosphate 65-47-4 ≥98.0%
    Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
    Cytidine-5'-triphosphate
  • HY-F0002
    NADP sodium salt 1184-16-3 99.43%
    NADP sodium salt (Sodium NADP), a nicotinamide adenine dinucleotide, is a redox cofactor. NADP sodium salt is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH).
    NADP sodium salt
  • HY-113325
    NADP 53-59-8 98.59%
    NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH).
    NADP
  • HY-B2176A
    ATP disodium trihydrate 51963-61-2 ≥98.0%
    ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation.
    ATP disodium trihydrate
  • HY-W013093
    Uridine triphosphate trisodium salt 19817-92-6
    Uridine triphosphate trisodium salt is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
    Uridine triphosphate trisodium salt
  • HY-W010970
    5'-Guanylic acid disodium salt 5550-12-9 ≥98.0%
    5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes.
    5'-Guanylic acid disodium salt
  • HY-145934
    UDP-GalNAz disodium 653600-61-4 99.78%
    UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor.
    UDP-GalNAz disodium
  • HY-W009162
    Cytidine 5'-monophosphate 63-37-6 99.96%
    Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5'-monophosphate
  • HY-W008661
    Deoxyguanosine triphosphate trisodium salt 93919-41-6 99.15%
    Deoxyguanosine triphosphate (dGTP) trisodium salt is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
    Deoxyguanosine triphosphate trisodium salt
  • HY-141567A
    Pseudouridine 5'-triphosphate trisodium 99.22%
    Pseudouridine-5’-triphosphate (Pseudo-UTP) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties.
    .
    Pseudouridine 5'-triphosphate trisodium
  • HY-W008915
    Cytidine 5'-diphosphate trisodium salt 34393-59-4 ≥98.0%
    Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA.
    Cytidine 5'-diphosphate trisodium salt
  • HY-W013159
    2'-Deoxyguanosine 5'-monophosphate disodium 33430-61-4 99.66%
    2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative.
    2'-Deoxyguanosine 5'-monophosphate disodium