UDP-GalNAc disodium
Based on 1 publication(s) in Google Scholar
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 108320-87-2
- Formula: C17H25N3Na2O17P2
- Molecular Weight:651.32
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) UDP-GalNAc disodium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
UDP-GalNAc (25 μM) disodium is used in in vitro glycosylation assays with purified ppGalNAc-T2 and T3[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 108320-87-2
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Appearance Solid
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Molecular Weight 651.32
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Formula C17H25N3Na2O17P2
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Color White to off-white
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3NC(C)=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
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Synonyms
UDP-N-acetyl-D-galactosamine disodium
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
H2O : 125 mg/mL (191.92 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Kaundinya CR, et al. In vitro characterization of N-terminal truncated EpsC from Bacillus subtilis 168, a UDP-N-acetylglucosamine 4,6-dehydratase. Arch Biochem Biophys. 2018 Nov 1;657:78-88. [Content Brief]
[2]. Hang HC, et al. Probing glycosyltransferase activities with the Staudinger ligation. J Am Chem Soc. 2004 Jan 14;126(1):6-7. [Content Brief]
[3]. Song L, et al. Inhibitor of ppGalNAc-T3-mediated O-glycosylation blocks cancer cell invasiveness and lowers FGF23 levels. Elife. 2017 Mar 31;6:e24051. [Content Brief]
[4]. Kohsaki T, et al. Expression of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase isozymes T1 and T2 in human colorectal cancer. J Gastroenterol. 2000;35(11):840-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.5353 mL | 7.6767 mL | 15.3534 mL | 38.3836 mL |
| 5 mM | 0.3071 mL | 1.5353 mL | 3.0707 mL | 7.6767 mL | |
| 10 mM | 0.1535 mL | 0.7677 mL | 1.5353 mL | 3.8384 mL | |
| 15 mM | 0.1024 mL | 0.5118 mL | 1.0236 mL | 2.5589 mL | |
| 20 mM | 0.0768 mL | 0.3838 mL | 0.7677 mL | 1.9192 mL | |
| 25 mM | 0.0614 mL | 0.3071 mL | 0.6141 mL | 1.5353 mL | |
| 30 mM | 0.0512 mL | 0.2559 mL | 0.5118 mL | 1.2795 mL | |
| 40 mM | 0.0384 mL | 0.1919 mL | 0.3838 mL | 0.9596 mL | |
| 50 mM | 0.0307 mL | 0.1535 mL | 0.3071 mL | 0.7677 mL | |
| 60 mM | 0.0256 mL | 0.1279 mL | 0.2559 mL | 0.6397 mL | |
| 80 mM | 0.0192 mL | 0.0960 mL | 0.1919 mL | 0.4798 mL | |
| 100 mM | 0.0154 mL | 0.0768 mL | 0.1535 mL | 0.3838 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
UDP-GalNAc disodium Related Classifications
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