2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. CNTF

CNTF

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Ciliary Neurotrophic Factor (CNTF) belongs to the IL-6 cytokine family. IL-6, IL-11 and CNTF are associated with cytokine trans signaling. CNTF shows a low affinity interaction with IL-6 receptor subunit alpha (IL-6Rα), leading to the formation and activation of the IL-6Rβ/gp130/LIFR signaling receptor complex[1]. CNTF is also an extracellular signaling protein in the neuroretinal and the interphotoreceptor matrix, which is associated with the membranes of the RPE, Muller and photoreceptor cells[2]. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. Because it promotes differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes under in vitro conditions and thus improves remyelination. Importantly, it also increases the survival of mature oligodendrocytes[3]. The similarity of human CNTF protein sequences to mice and rats was 81.82% and 84.0%, respectively.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72943
    CNTF Protein, Human (His)

    Ciliary neurotrophic factor; CNTF

    		Human E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Human (His) is produced by E. coli (A2-M200) with N-terminal His-tag.
  • HY-P72943AF
    Animal-Free CNTF Protein, Human (His)

    Ciliary neurotrophic factor; CNTF

    		Human E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. Animal-Free CNTF Protein, Human (His) is produced by E. coli (M1-M200) with C-terminal His-tag.
  • HY-P7145
    CNTF Protein, Human (HEK293)

    rHuCNTF; Ciliary Neurotrophic Factor

    		Human HEK293
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Human (HEK293) is produced by HEK293 cells (M1-M200) with tag free.
  • HY-P7147
    CNTF Protein, Mouse

    rMuCNTF; Ciliary Neurotrophic Factor

    		Mouse E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Mouse is produced by E. coli (A2-M198) with tag free.
  • HY-P7148
    CNTF Protein, Rat

    rRtCNTF; Ciliary Neurotrophic Factor

    		Rat E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Rat is produced by E. coli (A2-M200) with tag freeg.
  • HY-P7146
    CNTF Protein, Human

    rHuCNTF; Ciliary Neurotrophic Factor

    		Human E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Human is produced by E. coli (A2-M200) with tag free.
  • HY-P74242
    CNTF Protein, Mouse (His)

    Ciliary neurotrophic factor; CNTF

    		Mouse E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Mouse (His) is produced by E. coli (A2-M198) with N-terminal His-tag.
  • HY-P74242AF
    Animal-Free CNTF Protein, Mouse (His)

    Ciliary neurotrophic factor; CNTF

    		Mouse E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. Animal-Free CNTF Protein, Mouse (His) is produced by E. coli (M1-M198)with C-terminal His-tag.
  • HY-P7148A
    CNTF Protein, Rat (His)

    rRtCNTF; Ciliary Neurotrophic Factor

    		Rat E. coli
    CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family. CNTF could protect retinal cone and rod photoreceptors. CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons. CNTF Protein, Rat (His) is produced by E. coli (A2-M200) with N-terminal 6*His-tag.
Cat. No. Product Name Effect Purity