CEACAM8/NCA-95/CD66b
CEACAM8, traditionally designated CD66b or NCA-95, is a granulocyte-specific member of the carcinoembryonic antigen family that is attached to the neutrophil surface by a glycosylphosphatidylinositol anchor. Its two N-terminal immunoglobulin-like domains mediate adhesion, and the molecule is rapidly released from activated neutrophils, making soluble CD66b a sensitive index of granulocyte activation. Because expression is confined to the granulocytic lineage, anti-CD66b antibodies are used to gate neutrophils in flow cytometry and to visualize myeloid cell infiltration in inflamed tissue. Recombinant CEACAM8 supports antibody specificity testing and neutrophil activation studies. CD66b carries abundant sialyl Lewis X glycans, enabling E-selectin-mediated interactions with activated endothelium.
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CEACAM8/NCA-95/CD66b Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
