2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-1 Rrp2

IL-1 Rrp2

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70603
    IL-1RL2 Protein, Human (HEK293, His)

    Interleukin-1 receptor-like 2; IL1RL2; IL-36 receptor; IL-36R; IL-1Rrp2; IL1R-rp2;

    		Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (HEK293, His) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IL-1RL2 Protein, Human (HEK293, His) is 318 a.a., with molecular weight of ~60.0 kDa.
  • HY-P70625
    IL-1RL2 Protein, Human (HEK293, Fc)

    Interleukin-1 receptor-like 2; IL1RL2; IL-36 receptor; IL-36R; IL-1Rrp2; IL1R-rp2;

    		Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-1RL2 Protein, Human (HEK293, Fc) is 318 a.a., with molecular weight of 80-110 kDa.
  • HY-P70748
    IL-1RL2 Protein, Mouse (A158V, HEK293, His)

    Interleukin-1 receptor-like 2; IL1RL2; IL-36 receptor; IL-36R; IL-1Rrp2; IL1R-rp2

    		Mouse HEK293
    The IL-1RL2 protein functions as a receptor for interleukin 36 (IL36A, IL36B, and IL36G) and upon binding forms a complex with the coreceptor IL1RAP. This IL-36 receptor complex plays a key role in activating NF-κ-B, MAPK, and other signaling pathways. IL-1RL2 Protein, Mouse (A158V, HEK293, His) is the recombinant mouse-derived IL-1RL2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IL-1RL2 Protein, Mouse (A158V, HEK293, His) is 317 a.a., with molecular weight of 50-70 kDa.
  • HY-P78145
    IL-1RL2 Protein, Human (Biotinylated, HEK293, His-Avi)

    IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

    		Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of IL-1RL2 Protein, Human (Biotinylated, HEK293, His-Avi) is 316 a.a., with molecular weight of 55-75 kDa.
  • HY-P78462
    IL-1RL2 Protein, Human (HEK293, His-Avi)

    IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

    		Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (HEK293, His-Avi) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IL-1RL2 Protein, Human (HEK293, His-Avi) is 316 a.a., with molecular weight of 60-70 kDa.
  • HY-P78547
    IL-1RL2 Protein, Human (C154S, C262S, HEK293, His)

    IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

    		Human HEK293
    IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (C154S, C262S, HEK293, His) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-His labeled tag and C154S, C262S mutation. The total length of IL-1RL2 Protein, Human (C154S, C262S, HEK293, His) is 318 a.a., with molecular weight of 56-67 kDa.
  • HY-P77698
    IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus (HEK293, His)

    IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

    		Cynomolgus HEK293
    L-36R is a member of the IL-1 receptor family that contains six receptor proteins that form four signaling complexes: IL-1RI, IL-18R, IL-33R, and IL-36R, and two decoy receptors and two negative regulators. IL-36R is a heterodimer that consists of a receptor subunit named IL-1Rrp2 (IL-1RL2) and a co-receptor subunit Interleukin-1 receptor accessory protein, IL-1RAcP. The receptor can recognize three different agonists, IL-36α, IL-36β, and IL-36γ (also known as IL-1F6, IL-1F8, and IL-1F9), to induce the expression of inflammatory cytokines. IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-1 Rrp2/IL-1 R6 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus (HEK293, His) is 316 a.a., with molecular weight of 60-70 kDa.
Cat. No. Product Name Effect Purity