2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. T Cell CD Proteins NK Cell CD Proteins Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. CD161/KLRB1

CD161/KLRB1

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Cat. No. Product Name / Synonyms Species Source
  • HY-P78085
    CD161 Protein, Human (Biotinylated, HEK293, His-Avi)

    KLRB1; CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; CD161; Ly59; NKR; NKRP1; NKR-P1; NKRP1ANKR

    		Human HEK293
    CD161 protein plays a crucial role in inhibiting NK cell toxicity by activating specific acid sphingomyelinase/SMPD1 and increasing ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T cell proliferation. CD161 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD161 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD161 Protein, Human (Biotinylated, HEK293, His-Avi) is 159 a.a., with molecular weight of 35-43 kDa.
  • HY-P72750
    CD161 Protein, Human (HEK293, Fc)

    Killer cell lectin-like receptor subfamily B member 1; NKR-P1A; CD161; KLRB1; CLEC5B

    		Human HEK293
    CD161 protein plays a crucial role in inhibiting NK cell toxicity by activating specific acid sphingomyelinase/SMPD1 and increasing ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T cell proliferation. CD161 Protein, Human (HEK293, Fc) is the recombinant human-derived CD161 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD161 Protein, Human (HEK293, Fc) is 159 a.a., with molecular weight of 55-70 kDa.
  • HY-P76831
    OCIL/CLEC2D Protein, Rat (HEK293, Fc)

    C-type lectin domain family 2 member D5; Osteoclast inhibitory lectin; Ocil; Clec2d5

    		Rat HEK293
    The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag. The total length of OCIL/CLEC2D Protein, Rat (HEK293, Fc) is 136 a.a., with molecular weight of 44-54 & 36 kDa, respectively.
  • HY-P77901
    OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi)

    C-type lectin domain family 2 member D; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; CLAX; LLT1; OCIL; CLEC2D

    		Human HEK293
    OCIL/CLEC2D Protein, as a receptor for KLRB1, safeguards target cells from natural killer cell-mediated lysis. It not only inhibits osteoclast formation and bone resorption but also regulates interferon-gamma release, indicating its immune and bone-related regulatory functions. Additionally, OCIL/CLEC2D can bind high molecular weight sulfated glycosaminoglycans, suggesting its involvement in interactions with extracellular components. Existing as a homodimer with disulfide linkages, its oligomeric form plays a crucial role in mediating immune protection and bone homeostasis. OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) is the recombinant human-derived OCIL/CLEC2D protein, expressed by HEK293, with N-hFc, N-Avi labeled tag. The total length of OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) is 132 a.a., with molecular weight of 68-78 kDa.
  • HY-P77592
    CD161 Protein, Cynomolgus (HEK293, His)

    KLRB1; CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; CD161; Ly59; NKR; NKRP1; NKR-P1; NKRP1ANKR

    		Cynomolgus HEK293
    CD161 Protein plays a crucial role in inhibiting NK cell cytotoxicity by activating specific acid sphingomyelinase/SMPD1, elevating ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T-cell proliferation. As a lectin, CD161 binds to Gal-alpha(1,3)Gal and N-acetyllactosamine epitopes, acting as a ligand for CLEC2D/LLT1. Existing as a homodimer, CD161 interacts with acid sphingomyelinase/SMPD1, contributing to its multifaceted immune regulatory functions. CD161 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD161 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD161 Protein, Cynomolgus (HEK293, His) is 161 a.a., with molecular weight of 38-48 kDa.
  • HY-P77593
    CD161 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi)

    KLRB1; CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; CD161; Ly59; NKR; NKRP1; NKR-P1; NKRP1ANKR

    		Cynomolgus HEK293
    CD161 Protein plays a crucial role in inhibiting NK cell cytotoxicity by activating specific acid sphingomyelinase/SMPD1, elevating ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T-cell proliferation. As a lectin, CD161 binds to Gal-alpha(1,3)Gal and N-acetyllactosamine epitopes, acting as a ligand for CLEC2D/LLT1. Existing as a homodimer, CD161 interacts with acid sphingomyelinase/SMPD1, contributing to its multifaceted immune regulatory functions. CD161 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is the recombinant cynomolgus-derived CD161 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD161 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is 161 a.a., with molecular weight of 37-42 kDa.
  • HY-P77902
    OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi)

    LLT-1; CLAX; LLT1; OCIL; CLEC2D; CLAXLLT-1; OCILmember D

    		Human HEK293
    The OCIL/CLEC2D protein acts as a receptor for KLRB1 and protects target cells from natural killer cell-mediated lysis. It not only inhibits osteoclast formation and bone resorption, but also regulates the release of interferon-γ, indicating that it has immune and bone-related regulatory functions. OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc, N-Avi labeled tag. The total length of OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) is 132 a.a., with molecular weight of 68-75 kDa.
Cat. No. Product Name Effect Purity