Art. -Nr.: HY-L091

Lipid Metabolism Compound Library

84 Cited Publications

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Based on 84 publication(s) in Google Scholar

Lipids are a fundamental class of organic molecules implicated in a wide range of biological processes, and based on this can be broadly classified into five categories: fatty acids, triacylglycerols (TAGs), phospholipids, sterol lipids and sphingolipids. Lipids play a crucial role in different metabolic pathways and cellular functions. Lipid metabolism is an important physiological process that is related to nutrient adjustment, hormone regulation, and homeostasis. Lipid metabolism dysregulation is associated with many diseases such as obesity, liver disease, aging and inflammation.

MCE offers a unique collection of 1,002 compounds related to lipid metabolism, which target relevant targets in the process of lipid metabolism, such as ATGL, MAGL, FAAH, acetyl-Coa Carboxylase, FASN, etc. MCE lipid metabolism compound library is a useful tool for research lipid metabolism and drug discovery of diseases related to lipid metabolism.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Description & Advantages
Product Details
- Formulation
- Layout
- Container
- Storage
- Shipping
Publications (84)
Documentation
Composition

Description & Advantages

• A unique collection of 1,002 small molecule compounds with associated with lipid metabolism modulating properties.

• Targeting more than 35 targets associated with lipid metabolism, such as ATGL, MAGL, FAAH, Acetyl-CoA Carboxylase, FASN, etc.

• A useful tool for the research of lipid metabolism and related diseases.

• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

• Structurally diverse, medicinally active, and cell permeable.

• Detailed compound information with structure, IC₅₀, and brief introduction.

• High purity and quality validated by NMR and LC/MS.

• All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 1,002 lipid metabolism compounds supplied as pre-dissolved Solutions or Solid

Solution: 968 compounds supplied in 10 mM solution, 32 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage

-80°C

Shipping

Blue ice or dry ice