Angiopoietin Like 2
Angiopoietin-like proteins (ANGPTLs) are identified as a family of proteins structurally similar to the angiopoietins. Eight ANGPTLs have been discovered, namely ANGPTL1 to ANGPTL8. ANGPTLs do not bind to the receptors classically targeted by angiopoietins, Tie-1/2, and have been generally considered orphan ligands. Similar to angiopoietins, ANGPTLs are able to potently regulate angiogenesis.
Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. For example, ANGPTL 2, 3, 4, 6 and 7 are pro-inflammatory factors and regulate cancer progression, while ANGPTL1 inhibits tumor angiogenesis and metastasis.
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Angiopoietin Like 2 Recombinant Proteins (5)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
