2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Angiopoietins
  5. Angiopoietin Like 2

Angiopoietin Like 2

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Angiopoietin-like proteins (ANGPTLs) are identified as a family of proteins structurally similar to the angiopoietins. Eight ANGPTLs have been discovered, namely ANGPTL1 to ANGPTL8. ANGPTLs do not bind to the receptors classically targeted by angiopoietins, Tie-1/2, and have been generally considered orphan ligands. Similar to angiopoietins, ANGPTLs are able to potently regulate angiogenesis.
Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. For example, ANGPTL 2, 3, 4, 6 and 7 are pro-inflammatory factors and regulate cancer progression, while ANGPTL1 inhibits tumor angiogenesis and metastasis.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P78380
    ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His-Avi)

    ARP2; HARP; angiopoietin-like 2; ANGPTL2; ANGRP2; MGC8889

    		Human HEK293
    ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His-Avi) is 234 a.a., with molecular weight of 31-35 kDa.
  • HY-P75577
    ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His)

    Angiopoietin-related protein 2; ANGPTL2; ANGRP2; ARP2HARP; MGC8889

    		Human HEK293
    ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is 249 a.a., with molecular weight of ~34 kDa.
  • HY-P75578
    ANGPTL2/Angiopoietin-like 2 Protein, Mouse (HEK293, Fc)

    Angiopoietin-related protein 2; ANGPTL2; ANGRP2; ARP2HARP; MGC8889

    		Mouse HEK293
    ANGPTL2/Angiopoietin-like 2 protein plays a crucial role in inducing sprouting in endothelial cells through autocrine and paracrine mechanisms. It orchestrates angiogenic processes and regulates vascular development. ANGPTL2's versatile impact on endothelial cell behavior positions it as a key modulator in the molecular signals governing angiogenesis. ANGPTL2/Angiopoietin-like 2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Mouse (HEK293, Fc) is 249 a.a., with molecular weight of ~58 kDa.
  • HY-P78060
    ANGPTL2/Angiopoietin-like 2 Protein, Human (Biotinylated, HEK293, His-Avi)

    ARP2; HARP; angiopoietin-like 2; ANGPTL2; ANGRP2; MGC8889

    		Human HEK293
    ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (Biotinylated, HEK293, His-Avi) is 234 a.a., with molecular weight of 31-35 kDa.
  • HY-P71652
    ANGPTL2/Angiopoietin-like 2 Protein, Human (His-SUMO)

    Angiopoietin like 2; Angiopoietin related protein 2 ; Angiopoietin-like protein 2; Angiopoietin-related protein 2; HARP; MGC8889; UNQ170/PRO196

    		Human E. coli
    ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (His-SUMO) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (His-SUMO) is 471 a.a., with molecular weight of ~70.8 kDa.
Cat. No. Product Name Effect Purity