IFITM1/CD225
IFITM1, assigned CD225, is the shortest member of the interferon-induced transmembrane protein family, a cluster of small two-pass membrane proteins strongly induced by type I and type II interferons. Whereas IFITM3 resides mainly in endosomes and restricts influenza entry, IFITM1 accumulates at the plasma membrane and preferentially inhibits infection by enveloped viruses such as West Nile and SARS coronavirus through effects on membrane fusion. Historically known as 9-27 and Leu13, the molecule is abundant on endothelial cells and germ cell tumors, and IFITM1 expression in tumor cells can blunt oncolytic virus infection.
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IFITM1/CD225 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
