1. Natural Products
  2. Cyclopeptides


Cyclopeptides (16):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-A0279A
    Pristinamycin IA 3131-03-1 98.91%
    Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycoprotein and inhibits its function. Pristinamycin IA is active against StaphyloEoccus and Srreptococcus.
    Pristinamycin IA
  • HY-N1476
    Heterophyllin B 145459-19-4 99.88%
    Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer.
    Heterophyllin B
  • HY-P0027
    Jasplakinolide 102396-24-7 ≥99.0%
    Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity.
  • HY-N6690
    Destruxin B 2503-26-6 99.86%
    Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis, not only in vitro but also in vivo.
    Destruxin B
  • HY-N6689
    Destruxin A 6686-70-0
    Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities.
    Destruxin A
  • HY-P3055
    Dendrotoxin-I 107950-33-4
    Dendrotoxin-I is a potent K+ channels blocker and targets voltage-gated potassium channel subunits KV1.1 and KV1.2. Dendrotoxin-I is a neurotoxin isolated from thevenom of Dendroaspis snakes.
  • HY-N10473
    Pulcherriminic acid 957-86-8
    Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries.
    Pulcherriminic acid
  • HY-107245
    Segetalin B 164991-89-3 99.60%
    Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity.
    Segetalin B
  • HY-129077
    FR179642 168110-44-9 99.97%
    FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379.
  • HY-119640
    Aspercolorin 29123-52-2
    Aspercolorin, a secondary metabolite, is a cyclic peptide.
  • HY-N10185
    Cyclo(D-Ala-L-Pro) 36238-64-9
    Cyclo(D-Ala-L-Pro) is a cyclodipeptide.
  • HY-N6748
    Roquefortine C 58735-64-1
    Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria.
    Roquefortine C
  • HY-N10793
    RA-XI 143277-27-4
    RA-XI is a bicyclic hexapeptide isolated from Rubia cordifolia with antitumour activity.
  • HY-N10790
    RA-V 64725-24-2 99.58%
    RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
  • HY-P3107
    Homodestcardin 917382-84-4
    Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM.
  • HY-N144684
    Himastatin 126775-74-4
    Himastatin is a antitumor antibiotic produced by a strain of S. hygroscopicus sp. Himastatin is a dimeric cyclohexadepsipeptide containing piperazic acid and a unique central aromatic core.