1. Recombinant Proteins
  2. Receptor Proteins
  3. Receptor Tyrosine Phosphatase

Receptor Tyrosine Phosphatase

Cat. No. Product Name / Synonyms Species Source
  • HY-P7887
    CD45 Protein, Human (552a.a, HEK293, His)

    rHuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C

    Human HEK293
    CD45 Protein, Human (HEK 293, His) is a type 1 transmembrane protein tyrosine phosphatase (PTPase) expressed by all the haematopoietic stem cells (HSCs) except that of erythrocytes and platelets.
  • HY-P7884
    CD45 Protein, Mouse (HEK293, His)

    rMuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C

    Mouse HEK293
    CD45/PTPRC Protein, Mouse (HEK 293, His) expresses in HEK293 with a His tag at the N-terminus. CD45 is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes. PTPRC is an essential regulator of T and B cell antigen receptor-mediated activation.
  • HY-P72916
    CD45 Protein, Mouse (HEK293, Fc)

    Receptor-type tyrosine-protein phosphatase C; L-CA; T200; PTPRC; CD45

    Mouse HEK293
    The CD45 protein is a multifunctional member of the protein tyrosine phosphatase family with heparan sulfate proteoglycan and heparin binding activity as well as protein tyrosine phosphatase activity. It plays a crucial role in lymphocyte differentiation, macromolecular metabolic processes, and signal transduction regulation. CD45 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD45 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD45 Protein, Mouse (HEK293, Fc) is 400 a.a., with molecular weight of ~130 kDa.
  • HY-P78196
    CD45 Protein, Human (Biotinylated, HEK293, His-Avi)

    L-CA; CD45; T200; PTPRC; B220; CD45R; GP180; LCA; LY5; EC 3.1.3.48

    Human HEK293
    Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of CD45 Protein, Human (Biotinylated, HEK293, His-Avi) is 391 a.a., with molecular weight of 80-110 kDa.
  • HY-P70847
    IA2 Protein, Human (293a.a, His)

    Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2; PTPRN; ICA3; ICA512

    Human E. coli
    The IA2 protein is critical in the vesicle-mediated secretion process and is essential for the accumulation of secretory vesicles in the hippocampus, pituitary gland, and pancreatic islets. IA2 is critical for insulin-related functions, ensuring normal levels of insulin-containing vesicles, preventing degradation and promoting glucose-stimulated insulin secretion. IA2 Protein, Human (293a.a, His) is the recombinant human-derived IA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IA2 Protein, Human (293a.a, His) is 293 a.a., with molecular weight of ~34.86 kDa.
  • HY-P70848
    IA2 Protein, Human (365a.a, His)

    Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2; PTPRN; ICA3; ICA512

    Human E. coli
    IA2 Protein is pivotal in vesicle-mediated secretory processes, crucial for secretory vesicle accumulation in the hippocampus, pituitary, and pancreatic islets. Essential for insulin-related functions, IA2 ensures normal insulin-containing vesicle levels, preventing degradation and promoting glucose-stimulated insulin secretion. IA2's influence extends to neurotransmitter regulation, required for normal norepinephrine, dopamine, and serotonin accumulation. In females, IA2 is uniquely essential for pituitary hormone accumulation and secretion. It also maintains normal renin expression. Despite lacking intrinsic enzyme activity, IA2 may regulate active protein-tyrosine phosphatases, like PTPRA, through dimerization. IA2's interaction with ICA512-TMF highlights its role in modulating insulin secretory granule dynamics and proposes a tethering mechanism to the actin cytoskeleton, dependent on UTRN and regulated by ICA512-CFF dimerization. IA2 Protein, Human (365a.a, His) is the recombinant human-derived IA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IA2 Protein, Human (365a.a, His) is 375 a.a., with molecular weight of 45-50 kDa.
  • HY-P70847A
    IA2 Protein, Human (293a.a, N-His)

    Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2; PTPRN; ICA3; ICA512

    Human E. coli
    IA2 Protein is pivotal in vesicle-mediated secretory processes, crucial for secretory vesicle accumulation in the hippocampus, pituitary, and pancreatic islets. Essential for insulin-related functions, IA2 ensures normal insulin-containing vesicle levels, preventing degradation and promoting glucose-stimulated insulin secretion. IA2's influence extends to neurotransmitter regulation, required for normal norepinephrine, dopamine, and serotonin accumulation. In females, IA2 is uniquely essential for pituitary hormone accumulation and secretion. It also maintains normal renin expression. Despite lacking intrinsic enzyme activity, IA2 may regulate active protein-tyrosine phosphatases, like PTPRA, through dimerization. IA2's interaction with ICA512-TMF highlights its role in modulating insulin secretory granule dynamics and proposes a tethering mechanism to the actin cytoskeleton, dependent on UTRN and regulated by ICA512-CFF dimerization. IA2 Protein, Human (293a.a, N-His) is the recombinant human-derived IA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IA2 Protein, Human (293a.a, N-His) is 293 a.a., with molecular weight of ~35 kDa.
  • HY-P700968
    CD45 Protein, Human (HEK293, His-Avi)

    L-CA; CD45; T200; PTPRC; B220; CD45R; GP180; LCA; LY5; EC 3.1.3.48

    Human HEK293
    Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD45 Protein, Human (HEK293, His-Avi) is 391 a.a., with molecular weight of 80-110 kDa.
  • HY-P72915
    CD45 Protein, Mouse (sf9, His-GST)

    Receptor-type tyrosine-protein phosphatase C; L-CA; T200; PTPRC; CD45

    Mouse Sf9 insect cells
    CD45 Protein, a versatile member of the protein tyrosine phosphatase family, displays heparan sulfate proteoglycan and heparin binding activity, as well as protein tyrosine phosphatase activity. It plays a crucial role in lymphocyte differentiation, macromolecule metabolic processes, and signal transduction regulation. CD45 is associated with diseases such as systemic lupus erythematosus, hepatitis C, multiple sclerosis, and severe combined immunodeficiency. CD45 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived CD45 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CD45 Protein, Mouse (sf9, His-GST) is 700 a.a., with molecular weight of ~110 kDa.
  • HY-P76555
    PTP alpha/PTPRA Protein, Human (sf9, His-GST)

    Receptor-type tyrosine-protein phosphatase alpha; R-PTP-alpha; PTPA; PTPRL2

    Human Sf9 insect cells
    PTP alpha/PTPRA Protein, a tyrosine protein phosphatase, participates in integrin-mediated focal adhesion formation. Upon integrin engagement, it recruits BCAR3, BCAR1, and CRK to focal adhesions, promoting SRC-mediated phosphorylation of BRAC1. This leads to the activation of PAK and small GTPases RAC1 and CDC42. PTP alpha/PTPRA Protein, Human (sf9, His-GST) is the recombinant human-derived PTP alpha/PTPRA protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PTP alpha/PTPRA Protein, Human (sf9, His-GST) is 620 a.a., with molecular weight of ~90 kDa.
  • HY-P7887A
    CD45 Protein, Human (552a.a, HEK293, C-His)

    rHuReceptor-type tyrosine-protein phosphatase C/CD45, His; B220; CD45 antigen; CD45; CD45R; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, C; PTPRC; receptor-type tyrosine-protein phosphatase C

    Human HEK293
    Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (552a.a, HEK293, C-His) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD45 Protein, Human (552a.a, HEK293, C-His) is 552 a.a., with molecular weight (glycosylation form) of 130-180 kDa.
  • HY-P72914
    CD45 Protein, Mouse (sf9)

    Receptor-type tyrosine-protein phosphatase C; L-CA; T200; PTPRC; CD45

    Mouse Sf9 insect cells
    CD45 Protein, a versatile member of the protein tyrosine phosphatase family, displays heparan sulfate proteoglycan and heparin binding activity, as well as protein tyrosine phosphatase activity. It plays a crucial role in lymphocyte differentiation, macromolecule metabolic processes, and signal transduction regulation. CD45 is associated with diseases such as systemic lupus erythematosus, hepatitis C, multiple sclerosis, and severe combined immunodeficiency. CD45 Protein, Mouse (sf9) is the recombinant mouse-derived CD45 protein, expressed by Sf9 insect cells , with tag free. The total length of CD45 Protein, Mouse (sf9) is 700 a.a., with molecular weight of ~93 kDa.
Cat. No. Product Name Effect Purity