1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EGF Superfamily

EGF Superfamily

Epidermal growth factor (EGF) family is a group of growth factors with similar structural to EGF which is a potent mitogenic peptide. EGF family members include transforming growth factor-α (TGF-alpha), heparin-binding EGF-like growth factor (HB-EGF), amphiregulin, betacellulin, epiregulin, epigen, neuregulins 1-6. The biological effects of the EGF family members are mediated by the EGF receptor (EGFR/ErbB) tyrosine kinase family, which consists of four members: EGFR (ERBB1), ERBB2 (NEU/HER2 receptor), ERBB3, and ERBB4. EGF receptors are activated following the binding of ligands, and then activate signaling cascades that have many effects: cell proliferation, reduced apoptosis, and angiogenesis.

Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name Effect Purity