EGF Superfamily
Epidermal growth factor (EGF) family is a group of growth factors with similar structural to EGF which is a potent mitogenic peptide. EGF family members include transforming growth factor-α (TGF-alpha), heparin-binding EGF-like growth factor (HB-EGF), amphiregulin, betacellulin, epiregulin, epigen, neuregulins 1-6. The biological effects of the EGF family members are mediated by the EGF receptor (EGFR/ErbB) tyrosine kinase family, which consists of four members: EGFR (ERBB1), ERBB2 (NEU/HER2 receptor), ERBB3, and ERBB4. EGF receptors are activated following the binding of ligands, and then activate signaling cascades that have many effects: cell proliferation, reduced apoptosis, and angiogenesis.
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EGF Superfamily Recombinant Proteins (181)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
