1. Screening Libraries
  2. Angiogenesis Related Compound Library

Angiogenesis Related Compound Library

Cat. No.: HY-L088
Library Contents: XLSX PDF SDF

Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer).

MCE offers a unique collection of 1229 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

MCE Angiogenesis Related Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 1209 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution and 2 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock

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  • Description

  • Product Details

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Description
& Advantages

•   A unique collection of 1229 small molecule compounds with validated angiogenesis targets modulating properties.

•   Targeting more than 60 transcription factors, such as AP-1, ATF6, BCL6, NF-ΚB, etc.

•   A useful tool for the research of transcription factor-related regulation and diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 1229 epigenetics related compounds supplied as pre-dissolved Solutions or Solid.
Solution: 1209 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.
Storage:
-80°C
Shipping:
Blue ice
Composition

Angiogenesis Related Compound Library

Source: MedChem Express

Documentation

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    Product Name:
    Angiogenesis Related Compound Library
    Cat. No.:
    HY-L088
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack