1. Recombinant Proteins
  2. CD Antigens
  3. Epithelial cell CD Proteins

Epithelial cell CD Proteins

The cluster of differentiation (CD) antigens is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. Epithelial cells are cells that come from surfaces of your body, such as your skin, blood vessels, urinary tract, or organs. They act as a protective barrier. Receptor tyrosine-protein kinase erbB-2, also known as CD340, is a well-known epithelial tumor antigen.

 
Cat. No. Product Name / Synonyms Species Source
  • HY-P71963
    IL-17RA Protein, Human (HEK293, hFc)

    CANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262

    Human HEK293
    IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag. It consists of 288 amino acids (L33-W320).
  • HY-P73716
    PD-L1 Protein, Mouse (HEK293, His-Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of PD-L1 Protein, Mouse (HEK293, His-Fc) is 238 a.a., with molecular weight of 64-90 kDa.
  • HY-P72359
    CD47 Protein, Human (Biotinylated, HEK293, Avi-His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.
  • HY-P70632
    PD-L1 Protein, Mouse (HEK293, His)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PD-L1 Protein, Mouse (HEK293, His) is 220 a.a., with molecular weight of 38-58 kDa.
  • HY-P70633
    PD-L1 Protein, Mouse (220a.a, HEK293, Fc)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274;

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (220a.a, HEK293, Fc) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-L1 Protein, Mouse (220a.a, HEK293, Fc) is 220 a.a., with molecular weight of 66-90 kDa.
  • HY-P72824
    Aminopeptidase A Protein, Human (sf9, His)

    Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP

    Human Sf9 insect cells
    Aminopeptidase A protein has calcium-regulating activity and plays a key role in central hypertension by preferentially cleaving N-terminal acidic residues, including angiotensin II. The specificity of this enzyme highlights its involvement in the regulation of blood pressure-related peptides, suggesting potential implications for the physiological mechanisms of hypertension. Aminopeptidase A Protein, Human (sf9, His) is the recombinant human-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Human (sf9, His) is 917 a.a., with molecular weight of ~115.5 kDa.
  • HY-P7398
    PD-L1 Protein, Human (HEK293, His)

    rHuPD-L1, His; Programmed death ligand 1; CD274; B7-H1

    Human HEK293
    PD-L1 Protein, Human (HEK293, His) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P70010
    CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His)

    rHu5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE

    Human HEK293
    CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.
  • HY-P70325
    IL-4R alpha/CD124 Protein, Human (HEK293, mFc)

    rHuInterleukin-4 receptor subunit alpha/IL-4 RA, mFc; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal mFc-tag.
  • HY-P70652
    CD276/B7-H3 Protein, Human (433a.a, HEK293, His)

    CD276; B7H34Ig-B7-H3; B7-H3; B7 homolog 3; CD276 antigen; CD276 molecule; Costimulatory molecule

    Human HEK293
    CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 Protein, Human (433a.a, HEK293, His) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD276/B7-H3 Protein, Human (433a.a, HEK293, His) is 433 a.a., with molecular weight of 65-90 kDa.
  • HY-P70657
    PD-L1 Protein, Human (HEK293, mFc)

    Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1; Programmed Death Ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

    Human HEK293
    The PD-L1 protein critically regulates immune tolerance by acting as a ligand for PDCD1/PD-1, regulating T cell activation threshold, and limiting effector responses. It may act as a costimulatory molecule for IL10-producing T cell subsets. PD-L1 Protein, Human (HEK293, mFc) is the recombinant human-derived PD-L1 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of PD-L1 Protein, Human (HEK293, mFc) is 221 a.a., with molecular weight of 59-89 kDa.
  • HY-P70710
    IL-4R alpha/CD124 Protein, Human (HEK293, His)

    Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-H232) is produced in HEK293 cells with a C-Terminal His-tag.
  • HY-P70712
    IL-4R alpha/CD124 Protein, Human (HEK293, Fc)

    Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal hFc-tag.
  • HY-P70720
    CD24 Protein, Human (S44T, HEK293, Fc)

    Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A

    Human HEK293
    CD24 protein plays a pivotal role in cell differentiation across various cell types, with signaling potentially initiated by lectin-like ligand binding to CD24 carbohydrates, transduced through second messengers released from the GPI-anchor. CD24 also modulates B-cell activation responses, promoting AG-dependent B-cell proliferation and preventing terminal differentiation into antibody-forming cells. In association with SIGLEC10, CD24 contributes to the selective suppression of the immune response to DAMPs such as HMGB1, HSP70, and HSP90, suggesting a role in immune regulation. Additionally, CD24 is implicated in controlling autoimmunity, exhibiting cell-type-specific interactions with LYN and FGR in diverse cellular processes and immune regulation. CD24 Protein, Human (S44T, HEK293, Fc) is the recombinant human-derived CD24 protein, expressed by HEK293 , with C-hFc labeled tag and S44T mutation. The total length of CD24 Protein, Human (S44T, HEK293, Fc) is 33 a.a., with molecular weight of 40-55 kDa.
  • HY-P70820
    CD47 Protein, Mouse (HEK293, His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD47 Protein, Mouse (HEK293, His) is 140 a.a., with molecular weight of 30-60 kDa.
  • HY-P72374
    HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi)

    Proto-oncogene Neu; Tyrosine kinase-type cell surface receptor ERBB2; MLN19; NGL; TKR1

    Human HEK293
    The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 630 a.a., with molecular weight of 120-140 kDa.
  • HY-P72890
    CD21 Protein, Human (HEK293, His)

    Complement receptor type 2; Cr2; EBV receptor; CD21; C3DR

    Human HEK293
    CD21 Protein, a receptor for complement C3, Epstein-Barr virus, and HNRNPU, activates B lymphocytes and aids Epstein-Barr virus entry in microbial infection. Its engagement with these ligands highlights its vital role in immune responses and interactions, regulating B-cell activation and host defense against infections. CD21 Protein, Human (HEK293, His) is the recombinant human-derived CD21 protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of CD21 Protein, Human (HEK293, His) is 951 a.a., with molecular weight of 110-120 kDa.
  • HY-P72917
    CD47 Protein, Human (HEK293)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (HEK293) is the recombinant human-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Human (HEK293) is 121 a.a., with molecular weight of 35-48 kDa.
  • HY-P72918
    CD47 Protein, Mouse (Q61735-1, HEK293, His)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    The CD47 protein is an adhesive multifunctional protein that coordinates cell-cell interactions, serves as a THBS1 receptor, and regulates integrin signaling through heterotrimeric G proteins. It plays a key role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cell self-renewal, immune regulation, and memory formation. CD47 Protein, Mouse (Q61735-1, HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD47 Protein, Mouse (Q61735-1, HEK293, His) is 122 a.a., with molecular weight of 34-44 kDa.
  • HY-P72976
    CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc)

    Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4

    Human HEK293
    The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is 738 a.a., with molecular weight of 120-130 kDa.
Cat. No. Product Name Effect Purity