1. Recombinant Proteins
  2. PD-L1 Protein, Human (CHO, Fc)

PD-L1 Protein, Human (CHO, Fc)

Cat. No.: HY-P7397
Handling Instructions

PD-L1 Protein, Human (CHO, Fc) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
50 μg $210 In-stock
Estimated Time of Arrival: December 31
100 μg $350 Get quote
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rHuPD-L1, Fc Chimera; Programmed death ligand 1; CD274; B7-H1
Species

Human

Source

CHO

Accession

Q9NZQ7 (F19-T239)

Gene ID

29126

Molecular Weight

70-72 kDa

AA Sequence

FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERT

Biological Activity
1 µg/mL (100 µL/well) of immoblized recombinant human PD-L1/B7-H1-Fc can bind human Biotin-PD-1-Fc with a linear range of 0.1-1 μg/mL.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Programmed death-ligand 1 (PD-L1) has been speculated to play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the adaptive immune system reacts to antigens that are associated with immune system activation by exogenous or endogenous danger signals[1].

Documentation
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
PD-L1 Protein, Human (CHO, Fc)
Cat. No.:
HY-P7397
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