RSKL
The RSK-like group, RSKL1 (SgK496) and RSKL2 (SgK269), is a poorly characterized branch of the AGC family whose members retain the RSK-type tandem kinase-domain architecture but show limited similarity elsewhere in sequence. Present knowledge places them in the cytoplasm and nucleus with cell-type-restricted expression patterns; specific substrates and physiological roles remain largely undetermined, though genomic studies have associated the RSKL2 locus with carcinomas of the prostate, colon, and other epithelial tissues, and RSKL2 is reported to reside at epithelial cell-cell junctions. Because natural activators and downstream effectors are unresolved, recombinant RSKL proteins serve mainly in kinase-panel profiling, phosphoproteomic substrate screening, antibody generation, and functional studies aimed at defining this enigmatic AGC branch.
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RSKL Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
