SIRP alpha/CD172a
SIRP alpha, the CD172a antigen, is the prototypic signal regulatory protein, an inhibitory receptor whose cytoplasmic region carries ITIM motifs that recruit SHP phosphatases upon phosphorylation. Its extracellular IgV-like domain binds CD47, forming the CD47-SIRPalpha axis through which the widely expressed don't-eat-me signal prevents phagocytosis of healthy self cells. The receptor is expressed on myeloid cells, including macrophages and dendritic cells, and on neurons. Because many tumors amplify CD47 expression to evade macrophage clearance, disruption of the interaction with SIRP alpha, alone or combined with tumor antibodies, has become a prominent strategy in myeloid-directed cancer immunotherapy.
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SIRP alpha/CD172a Recombinant Proteins (35)
SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, Fc-Avi)
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Cat. No.: HY-P78211
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Rat (HEK293, His)
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Cat. No.: HY-P76073
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Human (HEK293, Fc)
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Cat. No.: HY-P7406
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Human (CAA71403, HEK293, His)
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Cat. No.: HY-P70484
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha V8/CD172a Protein, Human (AAH38510, HEK293, His)
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Cat. No.: HY-P76068
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha/CD172a Protein, Mouse (BAA20376, HEK293, Fc)
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Cat. No.: HY-P76071
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha V2/CD172a Protein, Human (HEK293, His)
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Cat. No.: HY-P77836
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Cynomolgus (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78553
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Human (HEK293, His, MALS verified)
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Cat. No.: HY-P70484U
Purity: ≥ 95%, as determined by reducing SDS-PAGE.; ≥ 90%, as determined by MALS.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha/CD172a Protein, Mouse (HEK293, His)
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Cat. No.: HY-P72468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha/CD172a Protein, Cynomolgus (HEK293, His)
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Cat. No.: HY-P72469
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Human (G75A, HEK293, His)
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Cat. No.: HY-P74546
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha/CD172a Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P72412
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha V4/CD172a Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P77843
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha V4/CD172a Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P77844
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phosphatase SHP Substrate 1; P84; Signal-Regulatory Protein Alpha-3; MFR; Signal-Regulatory Protein Alpha-2; SHPS-1; Signal-Regulatory Protein Alpha-1; CD172a; Signal-Regulatory Protein Alpha; MYD-1; SHP Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; CD172a Antigen; CD172 Antigen-Like Family Member A; Myd-1 Antigen; Inhibitory Receptor SHPS-1; MyD-1 Antigen; Macrophage Fusion Receptor; Sirp-Alpha-3; SIRP-ALPHA-1; Sirp-Alpha-2; SIRPalpha2; Sirp-Alpha-1; SIRPalpha; Bit; Signal Regulatory Protein Alpha; CDNA FLJ52934, Highly Similar To Tyrosine-Protein Phosphatase Non-Receptortype Substrate 1
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SIRP alpha V6/CD172a Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P77845
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha V6/CD172a Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P77846
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Human (HEK293, His-Myc)
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Cat. No.: HY-P7405
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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SIRP alpha/CD172a Protein, Mouse (G365D, HEK293, mFc)
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Cat. No.: HY-P78661
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIRPA; MYD1; Prev. PTPNS1; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; SHPS1; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; SIRP; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; BIT; Tyrosine Phos
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
