2. Biochemische Testreagenzien
  3. Gene Sequencing and Synthesis

Gene Sequencing and Synthesis

Nucleic acids are present in all living organisms and are categorized into two major types: ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). They serves as a carrier of genetic material,with DNA and RNA encode genetic information through nucleic acid sequences, thereby directing protein synthesis. Consequently, nucleic acids are the foundation of biological research.
MCE provides a variety of nucleic acid synthesis raw materials, including modified nucleotide materials, which can be used for nucleic acid biosynthesis, labeling, and gene sequencing.

 

Gene Sequencing and Synthesis (152):

Art. -Nr. Produktname CAS. Nr. Reinheit Chemische Struktur
  • HY-112582C
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) 3056945-59-3 99.70%
    N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability.
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM)
  • HY-114364
    UDP-Galactose disodium 137868-52-1 99.73%
    UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism.
    UDP-Galactose disodium
  • HY-40293
    N,N-Bis(trifluoromethylsulfonyl)aniline 37595-74-7 99.97%
    N,N-Bis(trifluoromethylsulfonyl)aniline (N-Phenyltrifluoromethanesulfonimide) is a sulfonylation reagent. N,N-Bis(trifluoromethylsulfonyl)aniline can be used for the synthesis of organic compounds.
    N,N-Bis(trifluoromethylsulfonyl)aniline
  • HY-130777A
    AMP-PNP lithium hydrate 99.98%
    AMP-PNP (Adenylyl imidodiphosphate) lithium hydrate is a non-hydrolyzable ATP analog. AMP-PNP lithium hydrate binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP lithium hydrate can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly.
    AMP-PNP lithium hydrate
  • HY-145974A
    m7GpppAmpG ammonium solution (100 mM) 3080642-79-8 99.96%
    m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5′ end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research.
    m7GpppAmpG ammonium solution (100 mM)
  • HY-114365
    UDP-GalNAc disodium 108320-87-2 99.98%
    UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer.
    UDP-GalNAc disodium
  • HY-156262
    DEPC-Treated Water
    DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity.
    DEPC-Treated Water
  • HY-113066C
    Guanosine 5'-diphosphate sodium, 96% (HPLC) 43139-22-6 99.88%
    Guanosine 5'-diphosphate (GDP) sodium, 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium, 96% (HPLC) is an iron mobilizer, which forms a complex with hepcidin to inhibit the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/stat-3 pathway. Guanosine 5'-diphosphate sodium, 96% (HPLC) ameliorates the Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4. Guanosine 5'-diphosphate sodium, 96% (HPLC) can be used in the research of AI.
    Guanosine 5'-diphosphate sodium, 96% (HPLC)
  • HY-145934A
    UDP-GlcNAz disodium 1611490-64-2 99.74%
    UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    UDP-GlcNAz disodium
  • HY-150145A
    Cy5-UTP sodium (10 mM in water) 99.26%
    Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP.
    Cy5-UTP sodium (10 mM in water)
  • HY-170224
    dNTP Mixture,10 mM Solution,PCR Grade 99.0%
    dNTP Mixture,10 mM Solution,PCR Grade is a PCR-grade 10 mM mixed solution of natural deoxynucleoside triphosphates (dATP, dCTP, dGTP, TTP), which is suitable for various biological reactions including DNA amplification and reverse transcription.
    dNTP Mixture,10 mM Solution,PCR Grade
  • HY-112582A
    N1-Methylpseudouridine-5′-triphosphate solution (100 mM) 1428903-59-6 99.88%
    N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
    N1-Methylpseudouridine-5′-triphosphate solution (100 mM)
  • HY-W008661
    Deoxyguanosine triphosphate trisodium solution (100 mM) 93919-41-6 99.95%
    Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
    Deoxyguanosine triphosphate trisodium solution (100 mM)
  • HY-141567A
    Pseudouridine 5'-triphosphate trisodium solution (100 mM) 98.0%
    Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection.
    Pseudouridine 5'-triphosphate trisodium solution (100 mM)
  • HY-107372A
    Uridine triphosphate trisodium dihydrate 116295-90-0
    Uridine triphosphate (trisodium dihydrate) (UTP (trisodium dihydrate); Uridine 5'-triphosphate (trisodium dihydrate)) is a biochemical reagent.
    Uridine triphosphate trisodium dihydrate
  • HY-34717
    Tetrabutylammonium tetrafluoroborate 429-42-5 99.93%
    Tetrabutylammonium tetrafluoroborate is an inorganic salt commonly used in organic synthesis reactions and electrochemical applications. It is usually used as a catalyst or reagent, and is widely used in the field of organic synthesis, such as fluorination reaction, olefin addition and cyclization reaction, etc. In addition, it can also be used in electrochemical deposition and electroplating, and plays an important role in some electronic devices. Although it has no direct application in the medical field, it plays an important role in chemical research and industrial production.
    Tetrabutylammonium tetrafluoroborate
  • HY-W013715A
    Deoxythymidine-5'-triphosphate trisodium solution (100 mM) 27821-54-1 98.06%
    Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
    Deoxythymidine-5'-triphosphate trisodium solution (100 mM)
  • HY-100767
    Guanylyl Imidodiphosphate trisodium 148892-91-5
    Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies.
    Guanylyl Imidodiphosphate trisodium
  • HY-136648A
    2'-Deoxyadenosine-5'-triphosphate trisodium 54680-12-5 98.0%
    2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
    2'-Deoxyadenosine-5'-triphosphate trisodium
  • HY-117813
    2-Thiouridine 20235-78-3 99.92%
    2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV).
    2-Thiouridine