GLP-1
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by post-translational processing of proglucagon in intestinal L cells and by preproglucagon neurons in the nucleus tractus solitarius. The active forms, mainly GLP-1(7-36)amide, are released within minutes of nutrient ingestion and act through the Gs-coupled GLP-1 receptor to augment glucose-dependent insulin secretion, suppress glucagon, slow gastric emptying and promote satiety via hypothalamic and vagal circuits. Because native GLP-1 is degraded within minutes by DPP-4, therapy relies on DPP-4-resistant analogs such as exenatide, liraglutide and semaglutide or on DPP-4 inhibitors; GLP-1-based drugs now anchor the treatment of type 2 diabetes and obesity, with proven cardiovascular benefit.
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GLP-1 Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
