2. Click Chemistry
  3. Tetrazine

Tetrazine

Tetrazine (142):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-130283
    Methyltetrazine-Ph-NHS ester 1644644-96-1 98.94%
    Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Methyltetrazine-Ph-NHS ester
  • HY-W053709A
    Tetrazine-Amine monohydrochloride 1416711-59-5 99.38%
    Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition. Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Amine monohydrochloride
  • HY-141269
    Methyltetrazine-PEG5-NHS ester 1802907-92-1
    Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
    Methyltetrazine-PEG5-NHS ester
  • HY-135140
    Methyltetrazine-amine 1345955-28-3 99.36%
    Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates.
    Methyltetrazine-amine
  • HY-141274
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol 58884-35-8
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
  • HY-180447
    Tz-Ph-PEG4-NH-DOTA 2756465-66-2
    Tz-Ph-PEG4-NH-DOTA (Compound 10) is a 1,2,4,5-tetrazine (Tz) derivative. Tz-Ph-PEG4-NH-DOTA can be used in PET imaging and tumor research.
    Tz-Ph-PEG4-NH-DOTA
  • HY-D3431
    CFSE-Tz
    CFSE-Tz
  • HY-D3418
    BOD-Tz-TMR
    BOD-Tz-TMR
  • HY-141278
    Methyltetrazine-PEG4-maleimide 1802908-02-6 98.61%
    Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Methyltetrazine-PEG4-maleimide
  • HY-136095
    Tetrazine-biotin 1714123-51-9 98.0%
    Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-biotin
  • HY-141263
    Methyltetrazine-acid 1380500-88-8 99.75%
    Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Methyltetrazine-acid
  • HY-130551
    Tetrazine-Ph-PEG5-NHS ester 1682653-80-0 99.29%
    Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Ph-PEG5-NHS ester
  • HY-136104
    Methyltetrazine-Maleimide 98.12%
    Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Methyltetrazine-Maleimide
  • HY-159794
    Azido-methyltetrazine di-arm linker 2861998-16-3 99.06%
    Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs).
    Azido-methyltetrazine di-arm linker
  • HY-140940
    Biotin-PEG4-methyltetrazine 1835759-81-3 99.18%
    Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Biotin-PEG4-methyltetrazine
  • HY-101460
    Tz-Thalidomide 2087490-42-2 98.60%
    Tz-Thalidomide is a tetrazine-tagged Thalidomide (HY-14658), an E3 ligase ligand. Tz-Thalidomide self-assembles with TCO-labeled target protein inhibitors, forming a CLIP-TAC (targeted protein degradation chimera) via click chemistry. This chimera recruits the E3 ubiquitin ligase CRBN to the target protein, thereby inducing ubiquitination and subsequent degradation of the target protein. When used in combination with JQ1-TCO (HY-148864), Tz-Thalidomide induces concentration-dependent degradation of BRD4 in cells. When combined with ERK-targeting protein inhibitors, Tz-Thalidomide induces degradation of ERK1/2 in cells. Tz-Thalidomide can be used in cancer-related research.
    Tz-Thalidomide
  • HY-124480
    Tetrazine-Ph-acid 1380500-92-4 98.67%
    Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Tetrazine-Ph-acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Ph-acid
  • HY-D1482
    Sulfo-Cy5-tetrazine 1801695-57-7
    Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Sulfo-Cy5-tetrazine
  • HY-138659
    Janelia Fluor® 646, Tetrazine 2042192-00-5
    Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Janelia Fluor® 646, Tetrazine
  • HY-130977
    Tetrazine-PEG4-amine hydrochloride 2752945-36-9 99.83%
    Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-PEG4-amine hydrochloride