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CY5

(Synonyms: Sulfo-Cyanine5)
46 Cited Publications
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Based on 46 publication(s) in Google Scholar

CY5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.

For research use only. We do not sell to patients.

  • Purity: 98.60%
  • CAS No.: 146368-11-8
  • Formula: C33H40N2O8S2
  • Molecular Weight:656.81
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)

  • CY5 Chemical Structure
    CY5 Chemical Structure
  • Experimental Validation Results for CY5
  • Experimental Validation Results for CY5
  • Experimental Validation Results for CY5
  • Experimental Validation Results for CY5
  • Experimental Validation Results for CY5
CAS No.: 146368-11-8
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • CY5 Chemical Structure
    CY5 Chemical Structure
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    CY5 purchased from MedChemExpress. Usage Cited in: ACS Nano. 2025 Dec 9;19(48):41368-41385. [Abstract]

    Customer Validation
     Cy5-MTFGM (1-10 mg/mL; i.t.; i.v.). Ex vivo FL imaging of major tissues at different time points after injection with Cy5-labeled MTFGM.

  • 1/16

    CY5 purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Oct 14;23(1):675. [Abstract]

    Customer Validation
     Cy5@CQM NPs (100 µL; CMn= 0.5 mM; intravenously injection). Immunofluorescence histology of lung tumors in mice at 30 min (left) and 2 h (right) p.i. of Cy5@CQM NPs. Dashed lines indicate tumor margins. Fluorescence labels: DAPI (blue), F4/80 (green), and Cy5@CQM NPs (red).

  • 1/16

    CY5 purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Oct 14;23(1):675. [Abstract]

    Customer Validation
     Cy5@CQM NPs (CMn= 0.1 mM; 1 h; 0.5-4 h). CLSM images of vesicle-mediated delivery from RAW264.7 cells to 4T1 cells, shown at various time points. Fluorescence labels: RAW264.7 cells and their extracellular vesicles (blue), 4T1 cells (green), and Cy5@CQM NPs (red). The white arrows indicate CQM NPs successfully delivered into 4T1 cells.

  • 1/16

    CY5 purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2025 Jan 7.

    Customer Validation
     Fluorescence of bone marrow from mice sacrificed 24 h after intravenous injection of PBS, equivalent Cy5 dissolved in PBS, Cy5 labeled exosomes.

  • 1/16

    CY5 purchased from MedChemExpress. Usage Cited in: ACS Nano. 2023 May 9;17(9):8204-8222. [Abstract]

    Customer Validation
     Cy5-HTSFcACE2 plasmid (5 μg/mL; 1-6 h). Nuclear localization and lysosomal escape of ACE2-CS-PRT@PM in PMVECs in hypoxia for the indicated periods (red, HTSFcACE2 plasmid labeled with Cy5; green, lysosome labeled with Lysotracker; blue, DAPI to stain the nuclei).

  • CY5