Decoy ODNs

The decoy oligodeoxynucleotides (ODNs) are short double-stranded DNA, and serves as a decoy sequence for a target transcription factor. Decoy ODNs blocking gene expression at the transcriptional level by competition for trans elements by mimicking cis elements within regulatory regions, which finally changes the target gene expression.

  • Decoy ODNs (5)

TFEB Decoy ODN sodium
TFEB Decoy ODN sodium
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5'-P-GAATTCCCGCCACGTGGTCAAAAGACCACGTGGCGGGAATTCCCCGACCACGTGGCAAAAGCCACGTGGTCGGG-3', sodium salt
Cat. No.: HY-148230
  • Molecular Weight: 22920.69 (free acid)

TFEB Decoy ODN sodium is a synthetic oligonucleotide with a hairpin ring structure, which were designed to inhibit Transcription factor EB (TFEB). TFEB decoy ODN inhibited fibrosis and autophagy in a UUO mouse model. The TFEB decoy ODNs also showed anti-inflammatory effects.

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Cupabimod
Cupabimod
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DNA, d(P-thio)(C-C-T-T-G-A-A-G-G-G-A-T-T-T-C-C-C-T-C-C), complex with DNA d(P-thio)(G-G-A-G-G-G-A-A-A-T-C-C-C-T-T-C-A-A-G-G) (1:1)
Cat. No.: HY-177624
CAS No.: 297774-48-2
Synonyms: AMG0103

Cupabimod is a decoy oligodeoxynucleotide for transcription factor NF-κB.

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Edifoligide
Edifoligide
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DNA, d(P-thio)(C-T-A-G-A-T-T-T-C-C-C-G-C-G), complex with DNA d(P-thio)(G-A-T-C-C-G-C-G-G-G-A-A-A-T) (1:1)
Cat. No.: HY-177627
CAS No.: 328538-04-1
Synonyms: CGT 003

Edifoligide is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure

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Edifoligide sodium
Edifoligide sodium
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DNA, d(P-thio)(C-T-A-G-A-T-T-T-C-C-C-G-C-G), complex with DNA d(P-thio)(G-A-T-C-C-G-C-G-G-G-A-A-A-T) (1:1), sodium salt
Cat. No.: HY-177627A
Synonyms: CGT 003 sodium

Edifoligide sodium is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure

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Cupabimod sodium
Cupabimod sodium
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DNA, d(P-thio)(C-C-T-T-G-A-A-G-G-G-A-T-T-T-C-C-C-T-C-C), complex with DNA d(P-thio)(G-G-A-G-G-G-A-A-A-T-C-C-C-T-T-C-A-A-G-G) (1:1), sodium salt
Cat. No.: HY-177624A
Synonyms: AMG0103 sodium

Cupabimod sodium is a decoy oligodeoxynucleotide for transcription factor NF-κB.

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