CD21/CR2
CD21, also known as complement receptor 2, is the product of the CR2 gene and functions as the B cell receptor for the C3dg and iC3b fragments of complement component C3. It is expressed on mature resting B cells and on follicular dendritic cells and, together with CD19 and CD81, forms the B cell co-receptor complex that lowers the activation threshold when the BCR engages C3d-opsonized antigen. CD21 also serves as the receptor used by Epstein-Barr virus to infect B lymphocytes. Loss of CD21 expression occurs in some B cell malignancies, and its staining pattern is used in immunophenotyping B cell lymphoproliferative disorders.
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CD21/CR2 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
