Preclinical Formulations

Nanoparticles generally refer to particles with dimensions at the nanometer scale, including polymer nanoparticles, lipid nanoparticles, and metal nanoparticles. Nanoparticles possess several important and unique characteristics, such as their surface to mass ratio that is much larger than that of other particles, their quantum properties and their ability to adsorb and carry other compounds. NPs have a relatively large (functional) surface which is able to bind, adsorb and carry other compounds such as drugs, probes and proteins. Therefore, nanoparticles can be applied in fields such as drug delivery, in vitro and in vivo diagnostics, nutritional supplements, and the production of biocompatibility-enhancing materials.

In the process of preclinical drug development, candidate compounds often encounter challenges such as poor water solubility, complex formulation procedures, and insufficient stability, which can delay research progress. To address these pain points, MCE has launched ready-to-use drug solution formulations. Relying on mature and standardized formulation processes, and customizing formulas based on the physicochemical properties of the compounds, MCE eliminates the need for cumbersome operations such as self-proportioning, dissolving, and pH adjustment, delivering standardized, highly adaptable, and stable solutions.

Animal diets are specially formulated feeds designed according to the species, age, and experimental purpose of laboratory animals, with precisely controlled ingredient composition and nutritional levels. Research diets serve as vehicles for delivering compounds such as drugs and inducers. Therefore, animal diets are widely applied in disease model establishment (e.g., obesity, diabetes, MASH/NASH, and atherosclerosis), pharmacodynamic evaluation, nutritional and metabolic studies, as well as microglia clearance and other mechanism research.