Signaling Pathway

Aldehyde Dehydrogenase (ALDH)

Aldehyde Dehydrogenase (ALDH)

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Aldehyde Dehydrogenase (ALDH) Inhibitors & Modulators (3)

Product Name Catalog No. Brief Description
Alda-1

HY-18936

Alda-1 is an ALDH2 agonist, cell-permeable activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).

Disulfiram

HY-B0240

Disulfiram is a carbamate derivative used as an alcohol deterrent.

NCT-501

HY-18768

NCT-501 is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM).