1. Recombinant Proteins
  2. Viral Proteins

A complete infectious virus particle, called a virion, consists of the nucleic acid (DNA or RNA) and an outer shell of protein. Viral proteins of the mature assembled virus particle, refer to viral structural protein, may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). In addition, the viral proteins also include nonstructural proteins, regulatory proteins and accessory proteins. Some of these proteins may play roles within the infected cell during virus replication or act in regulation of virus replication or virus assembly. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiology of COVID-19, is an enveloped, positive-sense single-stranded RNA β coronavirus of the family Coronaviridae. SARS-CoV-2 has 4 main structural proteins (S, E, M, and N) and 16 non-structural proteins (nsp1-16). MCE offers recombinant proteins derived from important viruses for virus research, including influenza virus,SARS-CoV-2 ,human immunodeficiency virus (HIV),cytomegalovirus (CMV),etc..

Cat. No. Product Name / Synonyms Species Source
  • HY-P72035
    SARS-CoV-2 S glycoprotein (HEK293, His, Flag)

    E2 Peplomer protein

    Virus HEK293
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (HEK293, His, Flag) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by HEK293 , with N-10*His, C-Flag labeled tag. The total length of SARS-CoV-2 S glycoprotein (HEK293, His, Flag) is 670 a.a., with molecular weight of ~120 kDa.
  • HY-P72038
    SARS-CoV-2 S glycoprotein (HEK293, His-mFc)

    Spike glycoproteinRBD; ,Spike Protein RBD;

    Virus HEK293
    The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. SARS-CoV-2 S glycoprotein (HEK293, His-mFc) is the recombinant Virus-derived SARS-CoV-2 S glycoprotein, expressed by HEK293 , with C-mFc, C-6*His labeled tag. The total length of SARS-CoV-2 S glycoprotein (HEK293, His-mFc) is 223 a.a., with molecular weight (glycosylation form) of ~66.0 kDa.
  • HY-P72045
    SARS-CoV S Protein (HEK293, His-Myc)

    S glycoprotein; E2; Peplomer protein; Spike protein S1; Spike protein S2;

    Virus HEK293
    The SARS-CoV S protein coordinates viral entry by interacting with human ACE2 and CLEC4M/DC-SIGNR receptors to attach viral particles to the cell membrane. It downregulates host tethering protein (BST2) through lysosomal degradation, antagonizing its antiviral activity. SARS-CoV S Protein (HEK293, His-Myc) is the recombinant Virus-derived SARS-CoV S protein, expressed by HEK293 , with N-10*His, C-Myc labeled tag. The total length of SARS-CoV S Protein (HEK293, His-Myc) is 222 a.a., with molecular weight of ~37 kDa.
  • HY-P73396
    SARS-CoV-2 S Protein RBD (HEK293)

    2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein; S protein RBD; 2019-nCoV S protein RBD

    Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein RBD (HEK293) is the recombinant Virus-derived SARS-CoV-2 S protein RBD, expressed by HEK293 , with tag free. The total length of SARS-CoV-2 S Protein RBD (HEK293) is 223 a.a., with molecular weight of approximately 34 kDa.
  • HY-P74445
    SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, His)

    SARS-CoV-2 Protein; SARS-CoV-2 Spike Protein

    Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 S1 protein, expressed by HEK293 , with C-His labeled tag. The total length of SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, His) is 670 a.a., with molecular weight of ~99.56 kDa.
  • HY-P73239
    NA/Neuraminidase Protein, Influenza A H5N1 (H255Y, HEK293)

    NA; Neuraminidase

    Virus HEK293
    Neuraminidase (NA) is described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. Whereby, NA facilitates viral invasion of the upper airways, facilitates virus release during virus budding, prevents self-aggregation and ensures the efficient spread of the progeny virus from cell to cell, and also plays a role in the determination of host range restriction on replication and virulence. NA/Neuraminidase Protein, Influenza A H5N1 (H255Y, HEK293) is the recombinant Virus-derived NA/Neuraminidase protein, expressed by HEK293 , with tag free. and H255Y mutation. The total length of NA/Neuraminidase Protein, Influenza A H5N1 (H255Y, HEK293) is 449 a.a., with molecular weight of ~49.2 kDa.
  • HY-P73957
    HA/Hemagglutinin Protein, Influenza B (A4D5Q0, sf9, His)

    HA; Hemagglutinin; HA/Hemagglutinin, Influenza B (B/Yamagata/16/1988, sf9, His)

    Virus Sf9 insect cells
    The Hemagglutinin (HA) protein crucially attaches virus particles to host cells by binding to sialic acid-containing receptors, inducing virion internalization through clathrin-dependent endocytosis. HA also facilitates an alternative clathrin- and caveolin-independent pathway for a portion of the virus particles. As a Class I viral fusion protein, HA mediates fusion between the virus particle's membrane and the endosomal membrane, vital for host range restriction and virulence determination, involving a low pH-triggered conformational change in HA2 and the release of the fusion hydrophobic peptide. HA/Hemagglutinin Protein, Influenza B (A4D5Q0, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of HA/Hemagglutinin Protein, Influenza B (A4D5Q0, sf9, His) is 546 a.a., with molecular weight of ~59 kDa.
  • HY-P74008
    HA/Hemagglutinin Protein, H5N1 (AAT76166, sf9, His)

    HA; Hemagglutinin; HA/Hemagglutinin Protein, H5N1 (A/chicken/Jilin/9/2004, sf9, His)

    Virus Sf9 insect cells
    HA/Hemagglutinin Protein is a viral membrane protein responsible for the initial steps of the entry of influenza virus into the host cell. It mediates binding of the virus particle to the host-cell membrane and catalyzes fusion of the viral membrane with that of the host. HA is pivotal in determining virus host range and virulence. HA/Hemagglutinin Protein, H5N1 (AAT76166, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of HA/Hemagglutinin Protein, H5N1 (AAT76166, sf9, His) is 531 a.a., with molecular weight of ~59.4 kDa.
  • HY-P74034
    HA/Hemagglutinin Protein, H1N1 (P03452, sf9, His)

    HA; Hemagglutinin; HA/Hemagglutinin Protein, H1N1 (A/Puerto Rico/8/1934, sf9, His)

    Virus Sf9 insect cells
    Hemagglutinin protein (HA) is a class I viral fusion protein that binds to sialic acid-containing receptors and initiates viral attachment to cells. This binding promotes internalization of virions through various endocytic pathways. HA/Hemagglutinin Protein, H1N1 (P03452, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of HA/Hemagglutinin Protein, H1N1 (P03452, sf9, His) is 528 a.a., with molecular weight of ~59.2 kDa.
  • HY-P74444
    SARS-CoV-2 S Protein (Omicron, B.1.1.529, His)

    SARS-CoV-2 Protein; SARS-CoV-2 Spike Protein

    Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by HEK293 , with C-His labeled tag. SARS-CoV-2 S Protein (Omicron, B.1.1.529, His), has molecular weight of ~136.67 kDa.
  • HY-P74447
    SARS-CoV-2 S Protein RBD (Omicron, B.1.1.529, His)

    SARS-CoV-2 RBD Protein; SARS-CoV-2 Spike RBD Protein; SARS-CoV-2 S Protein RBD

    Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein RBD (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 S protein RBD, expressed by HEK293 , with C-His labeled tag. The total length of SARS-CoV-2 S Protein RBD (Omicron, B.1.1.529, His) is 223 a.a., with molecular weight of ~26.83 kDa.
  • HY-P78106
    SARS-CoV-2 S Trimer Protein (Biotinylated, HEK293, His-Avi)

    S protein; Spike glycoprotein; S glycoprotein; COVID-19

    Virus HEK293
    SARS-CoV-2 S1 Protein, in its Spike protein S1 form, initiates infection by attaching the virion to the cell membrane through host receptor interaction. Simultaneously, Spike protein S2' acts as a viral fusion peptide, revealing itself after S2 cleavage during virus endocytosis. SARS-CoV-2 S Trimer Protein (Biotinylated, HEK293, His-Avi) is the recombinant Virus-derived SARS-CoV-2 S Trimer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of SARS-CoV-2 S Trimer Protein (Biotinylated, HEK293, His-Avi) is 1173 a.a., with molecular weight of 140-170 kDa.
  • HY-P78282
    SARS-COV-2 S Trimer Protein (HEK293, Fc)

    S protein; Spike glycoprotein; S glycoprotein; COVID-19

    Virus HEK293
    SARS-CoV-2 S1 Protein, in its Spike protein S1 form, initiates infection by attaching the virion to the cell membrane through host receptor interaction. Simultaneously, Spike protein S2' acts as a viral fusion peptide, revealing itself after S2 cleavage during virus endocytosis. SARS-COV-2 S Trimer Protein (HEK293, Fc) is the recombinant Virus-derived SARS-COV-2 S Trimer protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SARS-COV-2 S Trimer Protein (HEK293, Fc) is 1173 a.a., with molecular weight of 230-250 kDa.
  • HY-P78283
    SARS-COV-2 S Protein RBD (HEK293, His-Avi)

    S protein RBD; S glycoprotein RBD; Spike protein RBD

    Virus HEK293
    SARS-CoV-2 S1 Protein, in its Spike protein S1 form, initiates infection by attaching the virion to the cell membrane through host receptor interaction. Simultaneously, Spike protein S2' acts as a viral fusion peptide, revealing itself after S2 cleavage during virus endocytosis. SARS-COV-2 S Protein RBD (HEK293, His-Avi) is the recombinant Virus-derived SARS-COV-2 S protein RBD, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of SARS-COV-2 S Protein RBD (HEK293, His-Avi) is 214 a.a., with molecular weight of 32-42 kDa.
  • HY-P74445A
    SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, C-His)

    SARS-CoV-2 Protein; SARS-CoV-2 Spike Protein

    Virus HEK293
    The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, C-His) is the recombinant Virus-derived SARS-CoV-2 S1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, C-His) is 670 a.a., with molecular weight of ~130 kDa.
  • HY-P7436
    SARS-CoV-2 S1 Protein (HEK293)

    2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein; S protein RBD; 2019-nCoV S protein RBD

    Virus HEK293
    SARS-CoV-2 S1 Protein (HEK293) is the recombinant S1 protein produced in HEK293 cells.
  • HY-P72260
    Protein E6, HPV16 (His)

    E6; Protein E6

    Virus E. coli
    Protein E6 is one of three cancer proteins encoded by human papillomavirus (HPV). The binding of Protein E6 to ubiquitin protein ligase can inhibit the expression of p53. Protein E6 suppresses the immune response through the JAK-STAT signaling pathway. Protein E6 can promote cell proliferation and inhibit cell apoptosis. Protein E6, HPV16 (His) is the recombinant Virus-derived protein E6, HPV16, expressed by E. coli , with N-6*His labeled tag. The total length of Protein E6, HPV16 (His) is 158 a.a., the molecular weight are 22 KDa (monomer), 44 KDa (dimer), whiel dimers are generally formed.
  • HY-P72034
    SARS-CoV-2 Nucleocapsid Protein, Human (His)

    Nucleocapsid protein

    Human E. coli
    The SARS-CoV-2 nucleocapsid protein plays a crucial role in assembling the virion, forming the helical ribonucleocapsid (RNP), and interacting with the viral genome and membrane protein M. In addition to its structural function, it also enhances subgenomic viral RNA transcription and overall replication. SARS-CoV-2 Nucleocapsid Protein, Human (His) is the recombinant human-derived SARS-CoV-2 Nucleocapsid protein, expressed by E. coli , with N-6*His labeled tag. The total length of SARS-CoV-2 Nucleocapsid Protein, Human (His) is 419 a.a., with molecular weight of ~48 kDa.
  • HY-P70015
    B18R Protein, Vaccinia virus (HEK293, His)

    rVaSoluble interferon alpha/beta receptor B18/VACWR200, His; Soluble interferon alpha/beta receptor B18; VACWR200

    Virus HEK293
    B18R protein functions as a potent antagonist against the antiviral effects of host IFN-alpha/beta and key IFN-inducible proteins, such as OAS1 involved in viral RNA degradation. It acts as a soluble IFN-alpha receptor, effectively impeding the interaction between host IFN-alpha and its receptor. The protein's ability to interact with host IFNA1 underscores its role in modulating the host's immune response against viral infections. B18R Protein, Vaccinia virus (HEK293, His) is the recombinant Virus-derived B18R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B18R Protein, Vaccinia virus (HEK293, His) is 332 a.a., with molecular weight of 46-65 kDa.
  • HY-P72268
    Nucleoprotein/NP Protein, HCoV-NL63 (Sf9, His, myc)

    Protein N

    Virus Sf9 insect cells
    Nucleoprotein/NP proteins play a crucial role in assembling viral particles and facilitating the packaging of positive-strand viral genomic RNA into helical ribonucleocapsids (RNPs). Its interaction with the viral genome and membrane protein M is critical for virion assembly. Nucleoprotein/NP Protein, HCoV-NL63 (Sf9, His, myc) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by Sf9 insect cells , with C-Myc, N-10*His labeled tag. The total length of Nucleoprotein/NP Protein, HCoV-NL63 (Sf9, His, myc) is 377 a.a., with molecular weight of ~ 46.3 kDa.
Cat. No. Product Name Effect Purity