Protein Tyrosine Kinases
Tyrosine kinases are a family of enzymes, which catalyzes phosphorylation of select tyrosine residues in target proteins by using ATP as phosphate donor. Tyrosine kinases are primarily divided into receptor tyrosine kinase (RTK) such as EGFR, PDGFR, FGFR and the IR, and non-receptor tyrosine kinase (NRTK) such as SRC, ABL, FAK and Janus kinase. Of the 90 tyrosine kinases in human, 58 are receptor type, distributed into 20 classes. The 32 NRTKs can be placed in 10 classes. Tyrosine kinases are important mediators of the signaling cascade, determining key roles in diverse biological processes like growth, differentiation, adhesion, motility, metabolism and apoptosis in response to external and internal stimuli. In humans, it is reported that tyrosine kinases play significant roles in the development of many disease states, including diabetes and cancer. In addition, tyrosine kinase genes have also been linked to a wide variety of congenital syndromes.
- EGFR/ErbB family (113)
- FGFR (97)
- Eph Receptors (83)
- c-Met/HGFR (48)
- VEGFR (36)
- TAM Receptor (34)
- Trk Receptors (31)
- ROR family (27)
- PDGFR (22)
- DDR Family (21)
- Brutons Tyrosine Kinase (BTK) (19)
- TrkA (15)
- TrkB (13)
- TIE Receptors (11)
- Flt-3 (9)
- ABL1 (8)
- TrkC (5)
- JAK2 (5)
- Muscle-Specific Kinase (MuSK) (4)
- Janus Kinase 1 (JAK1) (4)
- Tyrosine-Protein Kinase CSK (3)
- Lymphocyte-Specific Protein Tyrosine Kinase (3)
- Breast Tumor Kinase (3)
- Janus Kinase 1 (JAK1) (3)
- Death-Associated Protein Kinase 1 (DAPK1) (2)
- Tyrosine-protein Kinase YES (2)
- FES Proto-Oncogene, Tyrosine Kinase (2)
- B Lymphoid Tyrosine Kinase (2)
- CDC-like kinase 3 (CLK3) (1)
- Death-Associated Protein Kinase 3 (DAPK3) (1)
- IL-2 Inducible T-Cell Kinase (ITK/TSK) (1)
- Activated Cdc42-Associated Kinase 1 (ACK1) (1)
- IL-2 Inducible T-Cell Kinase (ITK/TSK) (1)
More
-
Protein Tyrosine Kinases Recombinant Proteins (629)
EGFR Protein, Human (Active, sf9, His-GST)
0 Images
Cat. No.: HY-P72987
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
- Species:
- Source:
HER2/CD340 Protein, Human (HEK293)
0 Images
Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; Receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; Receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; Receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface Receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor Receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 Receptor Tyrosine Kinase 2; MLN 19
- Species:
- Source:
VEGFR-2 Protein, Human (HEK293, His)
0 Images
Cat. No.: HY-P70552
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDR; Fetal Liver Kinase 1; Kinase Insert Domain Receptor; Vascular Endothelial Growth Factor Receptor 2 Variant; Vascular Endothelial Growth Factor Receptor 2; Tyrosine Kinase Growth Factor Receptor; VEGFR2; Receptor Protein-Tyrosine Kinase; FLK1; Fetal L
- Species:
- Source:
EGFR Protein, Human (621a.a, HEK293, Fc)
0 Images
Cat. No.: HY-P74177
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein EGFR; Erb-B2 Receptor Tyrosine Kinase 1; Epidermal Growth Factor; Proto-Oncogene C-ErbB-1; EGFR VIII; HER1; NISBD2; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); NNCIS; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); PIG61; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; MENA; Epidermal Growth Factor Receptor Tyrosine Kinase Domain; Epidermal Growth Factor Receptor; Epidermal Growth Factor Receptor Variant EX12_15del
- Species:
- Source:
HER2/CD340 Protein, Human (Biotinylated, HEK293, His)
0 Images
Cat. No.: HY-P78882
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU;
- Species:
- Source:
Src Protein, Human (Active, sf9, His-GST)
0 Images
Cat. No.: HY-P73422
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRC; Tyrosine Kinase Pp60c-Src; Prev. SRC1; P60-Src; C-Src; Protooncogene SRC, Rous Sarcoma; ASV; Tyrosine-Protein Kinase SRC-1; V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-Src; Proto-Oncogene Tyrosine-Protein Kinase Src; THC6; SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase; Proto-Oncogene C-Src
- Species:
- Source:
VEGFR-2 Protein, Human (745a.a, HEK293, Fc)
0 Images
Cat. No.: HY-P70635
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDR; Fetal Liver Kinase 1; Kinase Insert Domain Receptor; Vascular Endothelial Growth Factor Receptor 2 Variant; Vascular Endothelial Growth Factor Receptor 2; Tyrosine Kinase Growth Factor Receptor; VEGFR2; Receptor Protein-Tyrosine Kinase; FLK1; Fetal L
- Species:
- Source:
EGFR Protein, Human (621a.a, CHO, His)
0 Images
Cat. No.: HY-P7340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
- Species:
- Source:
TrkC Protein, Human (HEK293, His)
0 Images
Cat. No.: HY-P73465
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK3; Neurotrophin 3 Receptor Truncated Isoform; Neurotrophic Receptor Tyrosine Kinase 3; Tyrosine-Protein Kinase Receptor; TRKC; Receptor Protein-Tyrosine Kinase; Neurotrophic Tyrosine Kinase, Receptor, Type 3; Tyrosine Kinase Receptor C; NT-3 Growth Fa
- Species:
- Source:
EGFR Protein, Human (Biotinylated, HEK293, His-Avi)
0 Images
Cat. No.: HY-P78118
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
- Species:
- Source:
HER2/CD340 Protein, Human (S310Y, HEK293, His)
0 Images
Cat. No.: HY-P78680
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU;
- Species:
- Source:
FGFR-1 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi)
0 Images
Cat. No.: HY-P77660
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
- Species:
- Source:
FGFR-4 Protein, Human (HEK293, Fc)
0 Images
Cat. No.: HY-P73057
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
- Species:
- Source:
HER2/CD340 Protein, Human (Biotinylated, HEK293, His-Avi)
0 Images
Cat. No.: HY-P78138
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU;
- Species:
- Source:
VEGFR-1 Protein, Human (HEK293, His-Avi)
0 Images
Cat. No.: HY-P78537
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FLT1; Tyrosine-Protein Kinase FRT; Prev. FLT; FLT-1; Vascular Endothelial Growth Factor Receptor 1; Vascular Endothelial Growth Factor Receptor 1 Variant; VEGFR1; Platelet-Derived Growth Factor Receptor-Like Protein; Vascular Permeability Factor Receptor;
- Species:
- Source:
FGFR-2 alpha (IIIb) Protein, Human (HEK293, His)
0 Images
Cat. No.: HY-P76336
Purity: ≥ 95%, as determined by reducing Bis-Tris PAGE.
Synonyms: FGFR2; Protein Tyrosine Kinase, Receptor Like 14; Prev. KGFR; Fibroblast Growth Factor Receptor; Prev. BEK; Receptor Protein-Tyrosine Kinase; Prev. CFD1; Craniofacial Dysostosis 1; Prev. JWS; Alternative Protein FGFR2; Keratinocyte Growth Factor Receptor;
- Species:
- Source:
FGFR-3 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi)
0 Images
Cat. No.: HY-P78124
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibrobla
- Species:
- Source:
TrkA Protein, Human (HEK293, His)
0 Images
Cat. No.: HY-P73457
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK1; Tyrosine Kinase Receptor A; Neurotrophic Receptor Tyrosine Kinase 1; P140-TrkA; TRKA; Gp140trk; TRK; Trk-A; MTC; Neurotrophic Tyrosine Kinase Receptor Type 1; High Affinity Nerve Growth Factor Receptor; Tyrosine-Protein Kinase Receptor; Neurotrophi
- Species:
- Source:
TrkB Protein, Human (HEK293, His-Fc)
0 Images
Cat. No.: HY-P73462
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTRK2; Neurotrophic Tyrosine Kinase, Receptor, Type 2, Isoform CRA_a; Neurotrophic Receptor Tyrosine Kinase 2; Neurotrophic Tyrosine Kinase, Receptor, Type 2; TRKB; Neurotrophin Receptor Tyrosine Kinase Type 2; BDNF/NT-3 Growth Factors Receptor; BDNF-Trop
- Species:
- Source:
FLT3 Protein, Human (T227M, HEK293, His)
0 Images
Cat. No.: HY-P75183
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLT3; CD135 Antigen; Fms Related Receptor Tyrosine Kinase 3; FLK-2; CD135; Growth Factor Receptor Tyrosine Kinase Type III; STK1; Receptor Protein-Tyrosine Kinase; FLK2; Fms-Related Tyrosine Kinase 3; Fms-Like Tyrosine Kinase 3; Fetal Liver Kinase 2; Rece
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
Capetin (28-54), human
0 Images
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
