1. Recombinant Proteins
  2. Complement System

Complement system, a major part of the innate immunity, is a cascade of soluble plasma proteins and membrane expressed receptors and regulators. Complement system operates in plasma, in tissues, on cell surface, and even within the cell. Complement system plays a key role in host homeostasis, inflammation, and in the defense against pathogens. Complement system can be activated through three main pathways: the classical pathway (CP), the lectin pathway (LP), and the alternative pathway (AP). These pathways depend on different molecules for their initiation, but they converge to generate the same set of terminal effector molecules: anaphylatoxins (C4a/C3a/C5a), the membrane attack complex (MAC), and opsonins (e.g., C3b). Complement system plays a key role in defense against pathogens and in host homeostasis.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7895
    Clusterin/APOJ Protein, Human (427a.a, HEK293, His)

    rHuClusterin/APOJ, His ; Clusterin; Aging-Associated Gene 4 Protein; Apolipoprotein J; Apo-J; Complement Cytolysis Inhibitor; CLI; Complement-Associated Protein SP-40; Ku70-Binding Protein 1; NA1/NA2; Testosterone-Repressed Prostate Message 2; TRPM-2; CLU; APOJ; CLI; KUB1

    Human HEK 293
    Clusterin/APOJ Protein, Human (HEK 293, His) expresses in HEK 293 cells with a His tag at the N-terminus. Clusterin (CLU) is a multifunctional glycoprotein that has been implicated in several physiological and pathological states, including Alzheimer’s disease (AD).
  • HY-P70485
    Vitronectin Protein, Human (459a.a, HEK 293, His)

    Vitronectin; VN; S-Protein; Serum-Spreading Factor; V75; VTN

    Human HEK293
  • HY-P7862
    Complement C3/C3a Protein, Human

    rHuComplement C3/C3a; Complement Component C3a; C3a; Anaphylatoxin

    Human E. coli
  • HY-P7535
    Clusterin/APOJ Protein, Human (HEK293, Fc-His)

    rHuApolipoprotein J, C-Fc-His; ApoJ; Clusterin; CLU; CLI; KUB1; Apolipoprotein J

    Human HEK 293
    Clusterin/APOJ Protein, Human (HEK293, Fc-His) expresses in HEK293 with an Fc fragment and a His tag at the N-terminus. Apolipoprotein J (ApoJ) is involved in numerous physiological process important for lipid transportation, vascular smooth muscle cell differentiation, and has the potential for atherosclerosis.
  • HY-P7863
    Complement C3/C3a Protein, Mouse

    rMuComplement C3/C3a; Complement Component C3a; Anaphylatoxin; C3a

    Mouse E. coli
  • HY-P73484
    Vitronectin Protein, Mouse (HEK293, His)

    Vitronectin; VN; S-Protein; Serum-Spreading Factor; V75; VTN

    Mouse HEK293
  • HY-P74614
    Protein S/PROS1 Protein, Human (HEK293, His)

    Vitamin K-dependent protein S; PROS1; PROS

    Human HEK293
  • HY-P7691
    CD93/C1qR1 Protein, Human (HEK293, His)

    rHuCD93, His; Complement Component C1q Receptor; Matrix-Remodeling-Associated Protein 4CD93; CD93

    Human HEK 293
    CD93/C1qR1 Protein, Human (HEK293, His) is a recombinant human CD93 produced in HEK293 cells, with His tag. CD93 is a type 1 transmembrane glycoprotein.
  • HY-P7695
    Complement C5/C5a Protein, Mouse

    rMuC5a; Complement C5; Hemolytic Complement; C5a

    Mouse E. coli
    Complement C5/C5a Protein, Mouse is a recombinant mouse complement component 5a (C5a). C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response.
  • HY-P7864
    Complement C5/C5a Protein, Human

    rHuComplement C5/C5a; Complement C5; C5a anaphylatoxin; C5a

    Human E. coli
    Complement C5/C5a Protein, Human is a recombinant human complement C5a. C5a is a 74-amino acid glycoprotein generated on activation of the C system. Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling.
  • HY-P70832
    HABP2 Protein, Human (HEK 293, His)

    Hyaluronan-binding protein 2; Factor VII-activating protease; Factor seven-activating protease; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding protein

    Human HEK293
  • HY-P70724
    Thrombomodulin Protein, Human (HEK 293, His)

    Thrombomodulin; THBD; TM; Fetomodulin; CD141; THRM

    Human HEK293
  • HY-P70031
    CFHR2 Protein, Human (252a.a, HEK293, His)

    rHuComplement factor H-related protein 2/CFHR2, His; Complement Factor H-Related Protein 2; FHR-2; DDESK59; H Factor-Like 3; H Factor-Like Protein 2; CFHR2; CFHL2; FHR2; HFL3

    Human HEK 293
  • HY-P71297
    Serpin G1 Protein, Mouse (HEK 293, His)

    SERPIN G1; Plasma protease C1 inhibitor; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; Serping1; C1nh

    Mouse HEK293
  • HY-P7692
    HABP1/C1QBP Protein, Human (His)

    rHuHABP1/C1QBP, His; Complement component 1 Q subcomponent-binding protein, mitochondrial; HABP1

    Human E. coli
    HABP1/C1QBP Protein, Human (His) is a recombinant human HABP1 (hyaluronan-binding protein 1)/C1QBP (complement component 1, q subcomponent binding protein) produced in HEK293 cells, with His tag. HABP1/C1QBP is a ubiquitously present glycoprotein having specific affinity towards hyaluronan (HA).
  • HY-P7813
    Complement Factor B/CFB Protein, Human (HEK293, His)

    rHuComplement Factor B, His; Complement Factor B; C3/C5 Convertase; Glycine-Rich Beta Glycoprotein; GBG; PBF2; Properdin Factor B; CFB; BF; BFD

    Human HEK 293
  • HY-P7861
    Complement Factor D/Adipsin Protein, Human (HEK293, His)

    rHuComplement Factor D/Adipsin, His; Complement factor D; CFD; Adipsin; C3 convertase activator; Properdin factor D; DF; PFD

    Human HEK 293
  • HY-P70055
    CFHR1 Protein, Human (HEK293, His)

    rHuComplement Factor H-related 1/CFHR1, His; Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2

    Human HEK 293
  • HY-P70102
    CFHR5 Protein, Human (HEK293, His)

    rHuComplement factor H-related protein 5/CFHR5, His; Complement factor H-related protein 5; CFHR5; CFHL5; FHR5

    Human HEK 293
  • HY-P71006
    VSIG4 Protein, Mouse (168a.a, HEK 293, His)

    Vsig4; V-set and immunoglobulin domain containing 4;

    Mouse HEK293
Cat. No. Product Name Effect Purity