2. Recombinant Proteins
  3. Complement System

Complement System

Complement System

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Complement system, a major part of the innate immunity, is a cascade of soluble plasma proteins and membrane expressed receptors and regulators. Complement system operates in plasma, in tissues, on cell surface, and even within the cell. Complement system plays a key role in host homeostasis, inflammation, and in the defense against pathogens. Complement system can be activated through three main pathways: the classical pathway (CP), the lectin pathway (LP), and the alternative pathway (AP). These pathways depend on different molecules for their initiation, but they converge to generate the same set of terminal effector molecules: anaphylatoxins (C4a/C3a/C5a), the membrane attack complex (MAC), and opsonins (e.g., C3b). Complement system plays a key role in defense against pathogens and in host homeostasis.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72946
    Complement factor H/CFH Protein, Human (372a.a, HEK293, His)

    Complement factor H; H factor 1; CFH; HF; HF1; HF2

    		Human HEK293
  • HY-P7861
    Complement Factor D/Adipsin Protein, Human (HEK293, His)

    rHuComplement Factor D/Adipsin, His; Complement factor D; CFD; Adipsin; C3 convertase activator; Properdin factor D; DF; PFD

    		Human HEK293
  • HY-P72020
    CD46 Protein, Human (HEK293, hFc)

    AHUS2; Antigen defined by monoclonal TRA 2 10; Antigen identified by monoclonal TRA 2 10; CD46; TRA2.10

    		Human HEK293
  • HY-P7861A
    Complement Factor D/Adipsin Protein, Human (HEK293, His, Solution)

    rHuComplement Factor D/Adipsin, His; Complement factor D; CFD; Adipsin; C3 convertase activator; Properdin factor D; DF; PFD

    		Human HEK293
  • HY-P7862
    Complement C3/C3a Protein, Human

    rHuComplement C3/C3a; Complement Component C3a; C3a; Anaphylatoxin

    		Human E. coli
  • HY-P7864
    Complement C5/C5a Protein, Human

    rHuComplement C5/C5a; Complement C5; C5a anaphylatoxin; C5a

    		Human E. coli
    Complement C5/C5a Protein, Human is a recombinant human complement C5a. C5a is a 74-amino acid glycoprotein generated on activation of the C system. Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling.
  • HY-P7863
    Complement C3/C3a Protein, Mouse

    rMuComplement C3/C3a; Complement Component C3a; Anaphylatoxin; C3a

    		Mouse E. coli
  • HY-P7695
    Complement C5/C5a Protein, Mouse

    rMuC5a; Complement C5; Hemolytic Complement; C5a

    		Mouse E. coli
    Complement C5/C5a Protein, Mouse is a recombinant mouse complement component 5a (C5a). C5a is a potent pro-inflammatory mediator and acts as an essential part of the innate immune response.
  • HY-P7691
    CD93/C1qR1 Protein, Human (HEK293, His)

    rHuCD93, His; Complement Component C1q Receptor; Matrix-Remodeling-Associated Protein 4CD93; CD93

    		Human HEK293
    CD93/C1qR1 Protein, Human (HEK293, His) is a recombinant human CD93 produced in HEK293 cells, with His tag. CD93 is a type 1 transmembrane glycoprotein.
  • HY-P70281
    MBL2/COLEC1 Protein, Human (HEK293, His)

    rHuMannose-binding protein C/MBL-2, His; Mannose-Binding Protein C; MBP-C; Collectin-1; MBP1; Mannan-Binding Protein; Mannose-Binding Lectin; MBL2; COLEC1; MBL

    		Human HEK293
  • HY-P72719
    CD59 Protein, Human (77a.a, HEK293, His)

    CD59 glycoprotein; HRF-20; MAC-IP; MACIF; MIRL; CD59; MIC11; MIN1; MSK21

    		Human HEK293
  • HY-P78005
    MASP2 Protein, Human (His)

    MAP19; MASP-2; MASP1P1; sMap

    		Human E. coli
  • HY-P7876
    Complement Factor D/Adipsin Protein, Mouse (234a.a, HEK293, His)

    rMuComplement Factor D/Adipsin, His; Complement factor D; 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Properdin factor D; Cfd; Adn; Df

    		Mouse HEK293
  • HY-P7890
    Complement factor H/CFH Protein, Human (367a.a, HEK293, His)

    rHuComplement factor H/CFH, His; Complement factor H; CFH

    		Human HEK293
    Complement factor H/CFH Protein, Human (367a.a, HEK 293, His) is a recombinant complement factor H (CFH) protein with His tag. Human complement factor H, a central complement control protein, is a member of the regulators of complement activation family.
  • HY-P71718
    C1QA Protein, Mouse (P.pastoris, His)

    C1qaComplement C1q subcomponent subunit A

    		Mouse P. pastoris
  • HY-P70031
    CFHR2 Protein, Human (252a.a, HEK293, His)

    rHuComplement factor H-related protein 2/CFHR2, His; Complement Factor H-Related Protein 2; FHR-2; DDESK59; H Factor-Like 3; H Factor-Like Protein 2; CFHR2; CFHL2; FHR2; HFL3

    		Human HEK293
  • HY-P7692
    HABP1/C1QBP Protein, Human (His)

    rHuHABP1/C1QBP, His; Complement component 1 Q subcomponent-binding protein, mitochondrial; HABP1

    		Human E. coli
    HABP1/C1QBP Protein, Human (His) is a recombinant human HABP1 (hyaluronan-binding protein 1)/C1QBP (complement component 1, q subcomponent binding protein) produced in HEK293 cells, with His tag. HABP1/C1QBP is a ubiquitously present glycoprotein having specific affinity towards hyaluronan (HA).
  • HY-P7813
    Complement Factor B/CFB Protein, Human (HEK293, His)

    rHuComplement Factor B, His; Complement Factor B; C3/C5 Convertase; Glycine-Rich Beta Glycoprotein; GBG; PBF2; Properdin Factor B; CFB; BF; BFD

    		Human HEK293
  • HY-P70674
    MBL2/COLEC1 Protein, Mouse (HEK293)

    Mannose binding lectin (C); isoform CRA_b; Mannose-binding protein C; Mbl2; MBL-2; Mannose Binding Lectin 2

    		Mouse HEK293
  • HY-P71726
    Complement Factor D/Adipsin Protein, Rat (P.pastoris, His)

    Cfd; Adn; Df; Complement factor D; EC 3.4.21.46; Adipsin; C3 convertase activator; Endogenous vascular elastase; Properdin factor D

    		Rat P. pastoris
Cat. No. Product Name Effect Purity