CA-125
null CA-125, the antigen defined by the OC125 antibody, is a high-molecular-mass epitope carried on the mucin MUC16, a huge transmembrane glycoprotein with numerous tandem repeats and sea urchin sperm protein domains. It is normally expressed by mesothelial cells of the pleura, pericardium, and peritoneum and by epithelia of the female reproductive tract, and its soluble ectodomain circulates in serum. Serum CA-125 measurement is the standard biomarker for monitoring epithelial ovarian cancer response and recurrence. CA-125/MUC16 also binds mesothelin, and its tumor expression continues to motivate antibody and CAR-T targeting strategies.
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CA-125 組換えタンパク質 (11)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- 分子式: Human
- 分子量: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
