Amphiregulin
Amphiregulin (AREG) is an epidermal growth factor (EGF)-like molecule and is classified into the EGF family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. AREG gene expression and release is induced by a plethora of stimuli including inflammatory lipids, cytokines, hormones, growth factors and xenobiotics. Through EGFR binding AREG activates the generation of intracellular signals modulating cell proliferation, apoptosis and migration of different cell types including epithelial cells, fibroblasts and immune cells (dendritic cells, neutrophils, mast cells and lymphocytes). Physiologically, AREG plays an important role in lung morphogenesis and the development and maturation of mammary glands, bone tissue and oocytes. AREG also plays a critical role in restoring tissue integrity following infection or injury.
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Amphiregulin Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
