1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Carboxypeptidase

Carboxypeptidase

Carboxypeptidase is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of aprotein or peptide. Contrast with an aminopeptidase, which cleaves peptide bonds at the other end of the protein. Humans, animals, and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation. Carboxypeptidases function involved in the indigestion of food, biosynthesis of neuroendocrine peptides, blood clotting, growth factor production, wound healing, reproduction, and many other processes.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100788
    2-PMPA
    Inhibitor ≥98.0%
    2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM.
    2-PMPA
  • HY-W044764
    2-Benzylsuccinic acid
    Inhibitor 99.41%
    2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA).
    2-Benzylsuccinic acid
  • HY-70005
    CPA inhibitor
    Inhibitor 99.93%
    CPA inhibitor (Carboxypeptidase inhibitor; compound 5) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.
    CPA inhibitor
  • HY-103345
    2-MPPA
    Inhibitor ≥98.0%
    2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM.
    2-MPPA
  • HY-139840A
    GCPII-IN-1 TFA
    Inhibitor 99.99%
    GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.
    GCPII-IN-1 TFA
  • HY-70003
    Carboxypeptidase G2 (CPG2) Inhibitor
    Inhibitor 98.03%
    Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
    Carboxypeptidase G2 (CPG2) Inhibitor
  • HY-W704574
    Mergetpa
    Inhibitor
    Mergetpa is a carboxypeptidase inhibitor used to block the conversion of kinins and B2 receptor antagonists to metabolites lacking the C-terminal arginine.
    Mergetpa
  • HY-137840
    Hippuryl-L-phenylalanine
    98.21%
    Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity.
    Hippuryl-L-phenylalanine
  • HY-P2981
    Carboxypeptidase C
    Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain.
    Carboxypeptidase C
  • HY-139840
    GCPII-IN-1
    Inhibitor
    GCPII-IN-1 is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.
    GCPII-IN-1
Cat. No. Product Name / Synonyms Species Source