1. Recombinant Proteins
  2. CD Antigens

The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The expression profiles of different CD antigens are distinguishing characteristics of the different progenitor populations and other cells that comprise the hematopoietic system. Thus, CD antigens are routinely used cell markers, allowing the identification of the presence and proportions of specific leukocyte cell populations and lymphocyte subsets, and their isolation, using combinations of fluorochrome-labeled antibodies and flow cytometry.

Cat. No. Product Name / Synonyms Species Source
  • HY-P71963
    IL-17RA Protein, Human (HEK293, hFc)

    CANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262

    Human HEK293
    IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag. It consists of 288 amino acids (L33-W320).
  • HY-P73716
    PD-L1 Protein, Mouse (HEK293, His-Fc)

    Programmed cell death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of PD-L1 Protein, Mouse (HEK293, His-Fc) is 238 a.a., with molecular weight of 64-90 kDa.
  • HY-P72359
    CD47 Protein, Human (Biotinylated, HEK293, Avi-His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.
  • HY-P70632
    PD-L1 Protein, Mouse (HEK293, His)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PD-L1 Protein, Mouse (HEK293, His) is 220 a.a., with molecular weight of 38-58 kDa.
  • HY-P7395
    PD-1 Protein, Human (CHO, Fc)

    rHuPD-1, Fc Chimera; PD1; CD279; PDCD1

    Human CHO
    PD-1 Protein, Human (CHO, Fc) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70633
    PD-L1 Protein, Mouse (220a.a, HEK293, Fc)

    Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274;

    Mouse HEK293
    PD-L1 protein serves as a ligand for the inhibitory receptor PDCD1/PD-1 and is critical for maintaining immune tolerance. This interaction modulates T cell activation, limits effector responses and may stimulate IL10-producing T cell subsets. PD-L1 Protein, Mouse (220a.a, HEK293, Fc) is the recombinant mouse-derived PD-L1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-L1 Protein, Mouse (220a.a, HEK293, Fc) is 220 a.a., with molecular weight of 66-90 kDa.
  • HY-P73309
    Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution)

    Neuropilin-1, His; CD304; NRP1; NRPNP1; VEGF165R; BDCA4

    Human HEK293
    Neuropilin-1 Protein plays a significant role by binding to VEGF-165, potentially inhibiting its cellular binding and inducing apoptosis. This dual functionality suggests its role in regulating VEGF-mediated processes. Interactions with semaphorin family members highlight its versatile ligand-binding capability. Neuropilin-1's expression adversely affects blood vessel number and integrity, suggesting a potential role in angiogenesis. Its diverse interactions underscore its importance in orchestrating complex cellular processes and implications in angiogenesis and apoptotic pathways. Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag and V179A mutation. The total length of Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is 623 a.a., with molecular weight of ~73.1 kDa.
  • HY-P7396
    PD-1 Protein, Human (143a.a, HEK293, His)

    rHuPD-1, His; PD1; CD279; PDCD1

    Human HEK293
    PD-1 Protein, Human (143a.a, HEK293, His) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P72824
    Aminopeptidase A Protein, Human (sf9, His)

    Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP

    Human Sf9 insect cells
    Aminopeptidase A protein has calcium-regulating activity and plays a key role in central hypertension by preferentially cleaving N-terminal acidic residues, including angiotensin II. The specificity of this enzyme highlights its involvement in the regulation of blood pressure-related peptides, suggesting potential implications for the physiological mechanisms of hypertension. Aminopeptidase A Protein, Human (sf9, His) is the recombinant human-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Human (sf9, His) is 917 a.a., with molecular weight of ~115.5 kDa.
  • HY-P70537
    CD4 Protein, Human (365a.a, HEK293, His)

    T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; sCD4

    Human HEK293
    The CD4 protein is an integral membrane glycoprotein that plays a key role in immune responses. In T cells, it serves as a coreceptor for MHC class II molecules, interacting with T cell receptors and initiating intracellular signaling pathways. CD4 Protein, Human (365a.a, HEK293, His) is the recombinant human-derived CD4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD4 Protein, Human (365a.a, HEK293, His) is 365 a.a., with molecular weight of 49-58 kDa.
  • HY-P70731
    CD38 Protein, Human (HEK293, His)

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38

    Human HEK293
    The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, His) is the recombinant human-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Human (HEK293, His) is 258 a.a., with molecular weight of 38-50 kDa.
  • HY-P70808
    CD40L/CD154/TRAP Protein, Mouse (HEK293, His)

    CD40 Ligand; CD40LG; HIGM1; T-B cell-activating molecule; T-BAM; TNFSF5; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5

    Mouse HEK293
    CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in mouse, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Mouse (HEK293, His) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal 6*His-tag.
  • HY-P7398
    PD-L1 Protein, Human (HEK293, His)

    rHuPD-L1, His; Programmed death ligand 1; CD274; B7-H1

    Human HEK293
    PD-L1 Protein, Human (HEK293, His) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.
  • HY-P7374
    IL-2R alpha/CD25 Protein, Human (HEK293, Fc)

    rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA

    Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, Fc) is a recombinant human IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).
  • HY-P7003
    BAFF/TNFSF13B Protein, Human (CHO)

    rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20

    Human CHO
    BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.
  • HY-P70807
    PVR/CD155 Protein, Human (HEK293, His)

    Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

    Human HEK293
    PVR/CD155 Protein, Human (HEK293, His) is a recombinant Human PVR expressed in HEK 293 cells with a His tag at the N-terminus. PVR, Human plays a role in cancer cell invasion and migration.
  • HY-P70824
    CD3 epsilon Protein, Human (27a.a, HEK293, Fc)

    T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    Human HEK293
    CD3 epsilon is an important component of the TCR-CD3 complex on T lymphocytes and promotes TCR-mediated signaling. When APC activates the TCR, CD3 epsilon, together with CD3D, CD3G, and CD3Z, transmits signals across the cell membrane through ITAMs. CD3 epsilon Protein, Human (27a.a, HEK293, Fc) is the recombinant human-derived CD3 epsilon protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CD3 epsilon Protein, Human (27a.a, HEK293, Fc) is 27 a.a., with molecular weight of 32-40 kDa.
  • HY-P7168
    Fas/CD95 Protein, Human (HEK293)

    rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1

    Human HEK293
    Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.
  • HY-P72022
    SLAMF2/CD48 Protein, Human (HEK293, hFc)

    B-lymphocyte activation marker BLAST-1 BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; BCM1; BLAST1;

    Human HEK293
    SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, hFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF2/CD48 Protein, Human (HEK293, hFc) is 194 a.a., with molecular weight of ~66 kDa.
  • HY-P7399
    PD-L2 Protein, Human (HEK293, Fc)

    rHuPD-L2, Fc Chimera; Programmed cell death 1 ligand 2; B7DC; CD273

    Human HEK293
    PD-L2 Protein, Human (HEK293, Fc), a second ligand for PD-1, interacts with PD-1 negatively regulates T cell proliferation, cytokine production and cytotoxic activity.
Cat. No. Product Name Effect Purity